GAMBACORTA, NICOLA
GAMBACORTA, NICOLA
DIPARTIMENTO DI BIOSCIENZE , BIOTECNOLOGIE E AMBIENTE
Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents
2021-01-01 Titov, Alexander A; Kobzev, Maxim S; Catto, Marco; Candia, Modesto de; Gambacorta, Nicola; Denora, Nunzio; Pisani, Leonardo; Nicolotti, Orazio; Borisova, Tatiana N; Varlamov, Alexey V; Voskressensky, Leonid G; Altomare, Cosimo D
Chalcones with N-Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study
2024-01-01 Jayan, Jayalakshmi; Trisciuzzi, Daniela; Benny, Feba; Kumar, Sunil; Gambacorta, Nicola; Catto, Marco; Abdelgawad, Mohamed A.; Ghoneim, Mohammed M.; Hamed Al-Serwi, Rasha; Gahtori, Prashant; Mary Zachariah, Subin; Nicolotti, Orazio; Bijo Mathew, And
Clinical course and management challenges in Lafora disease: a narrative analysis in an Apulian cohort
2025-01-01 D'Orsi, Giuseppe; Di Claudio, Maria Teresa; Liantonio, Antonella; Imbrici, Paola; Altomare, Cosimo Damiano; Palumbo, Orazio; Palumbo, Pietro; Benvenuto, Mario; Gambacorta, Nicola; Lolli, Graziano; Null, Null; Bisulli, Francesca; Costa, Cinzia; Damante, Giuseppe; Di Vito, Lidia; Imperatore, Valentina; Licchetta, Laura; Lodi, Raffaele; Muccioli, Lorenzo; Mantuano, Paola; Mazzone, Serena; Michelucci, Roberto; Pasini, Elena; Prontera, Paolo; Tappatà, Maria; Vignatelli, Luca; Zenesini, Corrado; Carella, Massimo
CRAT missense variants cause abnormal carnitine acetyltransferase function in an early-onset case of Leigh syndrome
2020-01-01 Laera, Luna; Punzi, Giuseppe; Porcelli, Vito; Gambacorta, Nicola; Trisolini, Lucia; Pierri, Ciro L; De Grassi, Anna
CUPID: A free drug discovery platform for the explainable multi-ion channel assessment of cardiotoxicity
2025-01-01 Gambacorta, Nicola; Mastrolorito, Fabrizio; Togo, Maria Vittoria; Amenduni, Vincenzo; Mele, Marco; Liantonio, Antonella; Mele, Antonietta; De Luca, Annamaria; Altomare, Cosimo Damiano; Belgiovine, Valentina; Tondo, Anna Rita; Cutropia, Francesca; Siragusa, Lydia; Amoroso, Nicola; Ciriaco, Fulvio; Imbrici, Paola; Trisciuzzi, Daniela; Nicolotti, Orazio
De Novo Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization
2020-01-01 Alberga, Domenico; Gambacorta, Nicola; Trisciuzzi, Daniela; Ciriaco, Fulvio; Amoroso, Nicola; Nicolotti, Orazio
Empagliflozin Repurposing for Lafora Disease: A Pilot Clinical Trial and Preclinical Investigation of Novel Therapeutic Targets
2025-01-01 D'Orsi, Giuseppe; Liantonio, Antonella; Imbrici, Paola; Gambacorta, Nicola; Dinoi, Giorgia; Altomare, Cosimo Damiano; DEFEAT-LD Study Group, DEFEAT-LD Study Group; Carella, Massimo
FAD/NADH Dependent Oxidoreductases: From Different Amino Acid Sequences to Similar Protein Shapes for Playing an Ancient Function
2019-01-01 Trisolini, Lucia; Gambacorta, Nicola; Gorgoglione, Ruggiero; Montaruli, Michele; Laera, Luna; Colella, Francesco; Volpicella, Mariateresa; De Grassi, Anna; Pierri, Ciro Leonardo
Informed Use of 3D-QSAR for the Rational Design of Coumarin Derivatives as Potent and Selective MAO B Inhibitors
2023-01-01 Gambacorta, N; Catto, M; Pisani, L; Carotti, A; Nicolotti, O
Isatin derived morpholine and piperazine derivatives as acetylcholinesterase inhibitors
2025-01-01 Thomas, Riya Rachel; Trisciuzzi, Daniela; Sudevan, Sachitra T.; Gambacorta, Nicola; Catto, Marco; Kumar, Sunil; Abdelgawad, Mohamed A.; El-Ghorab, Ahmed H.; Selim, Samy; Ghoneim, Mohammed M.; Zachariah, Subin Mary; Nicolotti, Orazio; Mathew, Bijo
Key Chemotypes for the Rational Design of Dual AChE/BACE-1 Inhibitors
2025-01-01 Davis, Densy; Trisciuzzi, Daniela; Sreekumar, Rajalakshmi; Binu Jacob, Maria; Madhu, Krishnadas; Gambacorta, Nicola; Catto, Marco; Parambi, Della Grace Thomas; Nicolotti, Orazio; Mathew, Bijo
New Insights Regarding Hemin Inhibition of the Purified Rat Brain 2-Oxoglutarate Carrier and Relationships with Mitochondrial Dysfunction
2022-01-01 Miniero, DANIELA VALERIA; Gambacorta, Nicola; Spagnoletta, Anna; Tragni, Vincenzo; Loizzo, Stefano; Nicolotti, Orazio; Pierri, CIRO LEONARDO; DE PALMA, Annalisa
Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease
2020-01-01 Purgatorio, Rosa; Gambacorta, Nicola; Catto, Marco; de Candia, Modesto; Pisani, Leonardo; Espargaró, Alba; Sabaté, Raimon; Cellamare, Saverio; Nicolotti, Orazio; Altomare, Cosimo D
PLATO: A Predictive Drug Discovery Web Platform for Efficient Target Fishing and Bioactivity Profiling of Small Molecules
2022-01-01 Ciriaco, Fulvio; Gambacorta, Nicola; Trisciuzzi, Daniela; Nicolotti, Orazio
The interaction of hemin, a porphyrin derivative, with the purified rat brain 2-oxoglutarate carrier
2021-01-01 Miniero, D. V.; Spagnoletta, A.; Gambacorta, N.; Scalera, V.; Pierri, C. L.; Nicolotti, O.; De Palma, A.
TIRESIA: An eXplainable Artificial Intelligence Platform for Predicting Developmental Toxicity
2023-01-01 Togo, Maria Vittoria; Mastrolorito, Fabrizio; Ciriaco, Fulvio; Trisciuzzi, Daniela; Tondo, Anna Rita; Gambacorta, Nicola; Bellantuono, Loredana; Monaco, Alfonso; Leonetti, Francesco; Bellotti, Roberto; Altomare, Cosimo Damiano; Amoroso, Nicola; Nicolotti, Orazio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents | 1-gen-2021 | Titov, Alexander A; Kobzev, Maxim S; Catto, Marco; Candia, Modesto de; Gambacorta, Nicola; Denora, Nunzio; Pisani, Leonardo; Nicolotti, Orazio; Borisova, Tatiana N; Varlamov, Alexey V; Voskressensky, Leonid G; Altomare, Cosimo D | |
| Chalcones with N-Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study | 1-gen-2024 | Jayan, Jayalakshmi; Trisciuzzi, Daniela; Benny, Feba; Kumar, Sunil; Gambacorta, Nicola; Catto, Marco; Abdelgawad, Mohamed A.; Ghoneim, Mohammed M.; Hamed Al-Serwi, Rasha; Gahtori, Prashant; Mary Zachariah, Subin; Nicolotti, Orazio; Bijo Mathew, And | |
| Clinical course and management challenges in Lafora disease: a narrative analysis in an Apulian cohort | 1-gen-2025 | D'Orsi, Giuseppe; Di Claudio, Maria Teresa; Liantonio, Antonella; Imbrici, Paola; Altomare, Cosimo Damiano; Palumbo, Orazio; Palumbo, Pietro; Benvenuto, Mario; Gambacorta, Nicola; Lolli, Graziano; Null, Null; Bisulli, Francesca; Costa, Cinzia; Damante, Giuseppe; Di Vito, Lidia; Imperatore, Valentina; Licchetta, Laura; Lodi, Raffaele; Muccioli, Lorenzo; Mantuano, Paola; Mazzone, Serena; Michelucci, Roberto; Pasini, Elena; Prontera, Paolo; Tappatà, Maria; Vignatelli, Luca; Zenesini, Corrado; Carella, Massimo | |
| CRAT missense variants cause abnormal carnitine acetyltransferase function in an early-onset case of Leigh syndrome | 1-gen-2020 | Laera, Luna; Punzi, Giuseppe; Porcelli, Vito; Gambacorta, Nicola; Trisolini, Lucia; Pierri, Ciro L; De Grassi, Anna | |
| CUPID: A free drug discovery platform for the explainable multi-ion channel assessment of cardiotoxicity | 1-gen-2025 | Gambacorta, Nicola; Mastrolorito, Fabrizio; Togo, Maria Vittoria; Amenduni, Vincenzo; Mele, Marco; Liantonio, Antonella; Mele, Antonietta; De Luca, Annamaria; Altomare, Cosimo Damiano; Belgiovine, Valentina; Tondo, Anna Rita; Cutropia, Francesca; Siragusa, Lydia; Amoroso, Nicola; Ciriaco, Fulvio; Imbrici, Paola; Trisciuzzi, Daniela; Nicolotti, Orazio | |
| De Novo Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization | 1-gen-2020 | Alberga, Domenico; Gambacorta, Nicola; Trisciuzzi, Daniela; Ciriaco, Fulvio; Amoroso, Nicola; Nicolotti, Orazio | |
| Empagliflozin Repurposing for Lafora Disease: A Pilot Clinical Trial and Preclinical Investigation of Novel Therapeutic Targets | 1-gen-2025 | D'Orsi, Giuseppe; Liantonio, Antonella; Imbrici, Paola; Gambacorta, Nicola; Dinoi, Giorgia; Altomare, Cosimo Damiano; DEFEAT-LD Study Group, DEFEAT-LD Study Group; Carella, Massimo | |
| FAD/NADH Dependent Oxidoreductases: From Different Amino Acid Sequences to Similar Protein Shapes for Playing an Ancient Function | 1-gen-2019 | Trisolini, Lucia; Gambacorta, Nicola; Gorgoglione, Ruggiero; Montaruli, Michele; Laera, Luna; Colella, Francesco; Volpicella, Mariateresa; De Grassi, Anna; Pierri, Ciro Leonardo | |
| Informed Use of 3D-QSAR for the Rational Design of Coumarin Derivatives as Potent and Selective MAO B Inhibitors | 1-gen-2023 | Gambacorta, N; Catto, M; Pisani, L; Carotti, A; Nicolotti, O | |
| Isatin derived morpholine and piperazine derivatives as acetylcholinesterase inhibitors | 1-gen-2025 | Thomas, Riya Rachel; Trisciuzzi, Daniela; Sudevan, Sachitra T.; Gambacorta, Nicola; Catto, Marco; Kumar, Sunil; Abdelgawad, Mohamed A.; El-Ghorab, Ahmed H.; Selim, Samy; Ghoneim, Mohammed M.; Zachariah, Subin Mary; Nicolotti, Orazio; Mathew, Bijo | |
| Key Chemotypes for the Rational Design of Dual AChE/BACE-1 Inhibitors | 1-gen-2025 | Davis, Densy; Trisciuzzi, Daniela; Sreekumar, Rajalakshmi; Binu Jacob, Maria; Madhu, Krishnadas; Gambacorta, Nicola; Catto, Marco; Parambi, Della Grace Thomas; Nicolotti, Orazio; Mathew, Bijo | |
| New Insights Regarding Hemin Inhibition of the Purified Rat Brain 2-Oxoglutarate Carrier and Relationships with Mitochondrial Dysfunction | 1-gen-2022 | Miniero, DANIELA VALERIA; Gambacorta, Nicola; Spagnoletta, Anna; Tragni, Vincenzo; Loizzo, Stefano; Nicolotti, Orazio; Pierri, CIRO LEONARDO; DE PALMA, Annalisa | |
| Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease | 1-gen-2020 | Purgatorio, Rosa; Gambacorta, Nicola; Catto, Marco; de Candia, Modesto; Pisani, Leonardo; Espargaró, Alba; Sabaté, Raimon; Cellamare, Saverio; Nicolotti, Orazio; Altomare, Cosimo D | |
| PLATO: A Predictive Drug Discovery Web Platform for Efficient Target Fishing and Bioactivity Profiling of Small Molecules | 1-gen-2022 | Ciriaco, Fulvio; Gambacorta, Nicola; Trisciuzzi, Daniela; Nicolotti, Orazio | |
| The interaction of hemin, a porphyrin derivative, with the purified rat brain 2-oxoglutarate carrier | 1-gen-2021 | Miniero, D. V.; Spagnoletta, A.; Gambacorta, N.; Scalera, V.; Pierri, C. L.; Nicolotti, O.; De Palma, A. | |
| TIRESIA: An eXplainable Artificial Intelligence Platform for Predicting Developmental Toxicity | 1-gen-2023 | Togo, Maria Vittoria; Mastrolorito, Fabrizio; Ciriaco, Fulvio; Trisciuzzi, Daniela; Tondo, Anna Rita; Gambacorta, Nicola; Bellantuono, Loredana; Monaco, Alfonso; Leonetti, Francesco; Bellotti, Roberto; Altomare, Cosimo Damiano; Amoroso, Nicola; Nicolotti, Orazio |