GHAFIR EL IDRISSI, IMANE
GHAFIR EL IDRISSI, IMANE
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
A novel cell-based assay to screen compounds which disrupts PrPC-Aβ1-42 oligomers interaction
2017-01-01 GHAFIR EL IDRISSI, Imane; Colabufo, Nicola Antonio; Beining, Chen
Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Abo–PrPC binding and downstream pathways
2021-01-01 Grayson, J. D.; Baumgartner, M. P.; Dos Santos Souza, C.; Dawes, S. J.; Ghafir El Idrissi, I.; Louth, J. C.; Stimpson, S.; Mead, E.; Dunbar, C.; Wolak, J.; Sharman, G.; Evans, D.; Zhuravleva, A.; Roldan, M. S.; Colabufo, N. A.; Ning, K.; Garwood, C.; Thomas, J. A.; Partrige, B. M.; de la Vega de Leon, A.; Gillet, V. J.; Rauter, A. P.; Chen, B.
COLD KITS BASED ON PSMA LIGANDS FOR THE PREPARATION OF RADIOPHARMACEUTICALS
2022-01-01 Denora, N.; La Forgia, R.; Cutrignelli, A.; Laquintana, V.; Lopedota, A. A.; Franco, M.; Lopalco, A.; Altomare, C. D.; Iacobazzi, R. M.; Coppa, A.; Ghafir El Idrissi, I.
Discovery of N-methylpiperazinyl flavones as a novel class of compounds with therapeutic potential against Alzheimer’s disease: synthesis, binding affinity towards amyloid β oligomers (Aβo) and ability to disrupt Aβo-PrPC interactions
2019-01-01 Matos, Ana M.; Man, Teresa; Idrissi, Imane; Souza, Cleide C.; Mead, Emma; Dunbar, Charlotte; Wolak, Joanna; Oliveira, Maria C.; Evans, David; Grayson, James; Partridge, Benjamin; Garwood, Claire; Ning, Ke; Sharman, Gary; Chen, Beining; Rauter, Amélia P.
Discovery of N-methylpiperazinyl flavones as a novel class of compounds with therapeutic potential against Alzheimer’s disease: synthesis, binding affinity towards amyloid β oligomers (Aβo) and ability to disrupt Aβo-PrPC interactions.
2019-01-01 Matos, Ana M.; Man, Teresa; Idrissi, Imane; Souza, Cleide C.; Mead, Emma; Dunbar, Charlotte; Wolak, Joanna; Oliveira, Maria C.; Evans, David; Grayson, James; Partridge, Benjamin; Garwood, Claire; Ning, Ke; Sharman, Gary; Rauter, Beining Chen and Amélia P.
Drug Discovery for Alzheimer’s Disease: Screen of small molecules able to inhibit PrPC-Abos interaction using ICC and the role of Cu2+ in this scenarios.
2018-01-01 GHAFIR EL IDRISSI, Imane; Colabufo, Nicola Antonio; Beining, Chen
Early Diagnosis of Alzheimer’s Disease by a Synergistic Evaluation of Free Copper Ion in the Serum and SPECT Analysis
2015-01-01 GHAFIR EL IDRISSI, Imane; Contino, Marialessandra; Olimpia, Difruscolo; Marcello, Lacriola; Giovanni, Basilisco; Colabufo, Nicola Antonio
Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease
2020-01-01 de Matos, Ana M; Blázquez-Sánchez, M Teresa; Bento-Oliveira, Andreia; de Almeida, Rodrigo F M; Nunes, Rafael; Lopes, Pedro E M; Machuqueiro, Miguel; Cristóvão, Joana S; Gomes, Cláudio M; Souza, Cleide S; El Idrissi, Imane G; Colabufo, Nicola A; Diniz, Ana; Marcelo, Filipa; Oliveira, M Conceição; López, Óscar; Fernandez-Bolaños, José G; Dätwyler, Philipp; Ernst, Beat; Ning, Ke; Garwood, Claire; Chen, Beining; Rauter, Amélia P
Liquid Biopsy beyond Cancer: A miRNA Detection in Serum with Electrochemical Chip for Non‐Invasive Coeliac Disease Diagnosis
2022-01-01 Caratelli, Veronica; Moccia, Maria; Paggioro, Francesca R.; Fiore, Luca; Avitabile, Concetta; Saviano, Michele; Imbriani, Anna Lisa; Dardano, Principia; DE LUCA, Stefano; Moscone, Danila; Colabufo, Nicola A.; Ghafir El Idrissi, Imane; Russo, Francesco; Riezzo, Giuseppe; Giannelli, Gianluigi; Arduini, Fabiana
Measurements of serum non-ceruloplasmin copper by a direct fluorescent methodspecific to Cu(II)
2017-01-01 Squitti, R; Siotto, M; Cassetta, E; El Idrissi, Ig; Colabufo, Nicola Antonio
Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures
2023-01-01 Tylek, Kinga; Trojan, Ewa; Leśkiewicz, Monika; GHAFIR EL IDRISSI, Imane; Lacivita, Enza; Leopoldo, Marcello; Basta-Kaim, Agnieszka
miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
2014-01-01 Gisel, Andreas; Valvano, Mirna; GHAFIR EL IDRISSI, Imane; Nardulli, Patrizia; Azzariti, Amalia; Carrieri, Antonio; Contino, Marialessandra; Colabufo, Nicola Antonio
Miscele di caffè per la neuroprotezione
2016-01-01 Colabufo, Na; Leopoldo, M; Berardi, F; Perrone, R; Cantore, M; Ghafir El Idrissi, I; Travaglio, D; Schino, I.
Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey
2024-01-01 Ghafir El Idrissi, I.; Santo, A.; Lacivita, E.; Leopoldo, M.
Non-ceruplasmin copper didtincts subtypes in Alzheimer's disease: a genetic study of ATP7B frequency
2017-01-01 Squitti, R; Ventriglia, M; Gennarelli, M; Colabufo, Nicola Antonio; Ghafir El Idrissi, I; Bucossi, S; Mariani, S; Rongioletti, M; Zanetti, O; Congiu, C; Rossini, Pm; Bonvicini, C.
P-GP RADIOTRACER FOR IMAGING AS BIOMARKERS INVOLVED IN ONSET OF NEURODEGENERATIVE DISEASE
2015-01-01 Ghafir El Idrissi, Imane; Cantore, Mariangela; Berardi, Francesco; Leopoldo, Marcello; Perrone, Roberto; Colabufo, Nicola Antonio
RATIONAL DESIGN AND SYNTHESIS OF POTENTIAL SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT) RADIOLIGANDS FOR IN VIVO IMAGING OF P2X7 RECEPTORS
2022-01-01 Ghafir El Idrissi, I.; Lacivita, E.; Dal, Ben; D., Volpini; R., Leopoldo
Structure-Activity Relationships and Therapeutic Potential of Purinergic P2X7 Receptor Antagonists
2024-01-01 GHAFIR EL IDRISSI, Imane; Podlewska, Sabina; Abate, Carmen; J Bojarski, Andrzej; Lacivita, Enza; Leopoldo, Marcello
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A novel cell-based assay to screen compounds which disrupts PrPC-Aβ1-42 oligomers interaction | 1-gen-2017 | GHAFIR EL IDRISSI, Imane; Colabufo, Nicola Antonio; Beining, Chen | |
| Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Abo–PrPC binding and downstream pathways | 1-gen-2021 | Grayson, J. D.; Baumgartner, M. P.; Dos Santos Souza, C.; Dawes, S. J.; Ghafir El Idrissi, I.; Louth, J. C.; Stimpson, S.; Mead, E.; Dunbar, C.; Wolak, J.; Sharman, G.; Evans, D.; Zhuravleva, A.; Roldan, M. S.; Colabufo, N. A.; Ning, K.; Garwood, C.; Thomas, J. A.; Partrige, B. M.; de la Vega de Leon, A.; Gillet, V. J.; Rauter, A. P.; Chen, B. | |
| COLD KITS BASED ON PSMA LIGANDS FOR THE PREPARATION OF RADIOPHARMACEUTICALS | 1-gen-2022 | Denora, N.; La Forgia, R.; Cutrignelli, A.; Laquintana, V.; Lopedota, A. A.; Franco, M.; Lopalco, A.; Altomare, C. D.; Iacobazzi, R. M.; Coppa, A.; Ghafir El Idrissi, I. | |
| Discovery of N-methylpiperazinyl flavones as a novel class of compounds with therapeutic potential against Alzheimer’s disease: synthesis, binding affinity towards amyloid β oligomers (Aβo) and ability to disrupt Aβo-PrPC interactions | 1-gen-2019 | Matos, Ana M.; Man, Teresa; Idrissi, Imane; Souza, Cleide C.; Mead, Emma; Dunbar, Charlotte; Wolak, Joanna; Oliveira, Maria C.; Evans, David; Grayson, James; Partridge, Benjamin; Garwood, Claire; Ning, Ke; Sharman, Gary; Chen, Beining; Rauter, Amélia P. | |
| Discovery of N-methylpiperazinyl flavones as a novel class of compounds with therapeutic potential against Alzheimer’s disease: synthesis, binding affinity towards amyloid β oligomers (Aβo) and ability to disrupt Aβo-PrPC interactions. | 1-gen-2019 | Matos, Ana M.; Man, Teresa; Idrissi, Imane; Souza, Cleide C.; Mead, Emma; Dunbar, Charlotte; Wolak, Joanna; Oliveira, Maria C.; Evans, David; Grayson, James; Partridge, Benjamin; Garwood, Claire; Ning, Ke; Sharman, Gary; Rauter, Beining Chen and Amélia P. | |
| Drug Discovery for Alzheimer’s Disease: Screen of small molecules able to inhibit PrPC-Abos interaction using ICC and the role of Cu2+ in this scenarios. | 1-gen-2018 | GHAFIR EL IDRISSI, Imane; Colabufo, Nicola Antonio; Beining, Chen | |
| Early Diagnosis of Alzheimer’s Disease by a Synergistic Evaluation of Free Copper Ion in the Serum and SPECT Analysis | 1-gen-2015 | GHAFIR EL IDRISSI, Imane; Contino, Marialessandra; Olimpia, Difruscolo; Marcello, Lacriola; Giovanni, Basilisco; Colabufo, Nicola Antonio | |
| Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease | 1-gen-2020 | de Matos, Ana M; Blázquez-Sánchez, M Teresa; Bento-Oliveira, Andreia; de Almeida, Rodrigo F M; Nunes, Rafael; Lopes, Pedro E M; Machuqueiro, Miguel; Cristóvão, Joana S; Gomes, Cláudio M; Souza, Cleide S; El Idrissi, Imane G; Colabufo, Nicola A; Diniz, Ana; Marcelo, Filipa; Oliveira, M Conceição; López, Óscar; Fernandez-Bolaños, José G; Dätwyler, Philipp; Ernst, Beat; Ning, Ke; Garwood, Claire; Chen, Beining; Rauter, Amélia P | |
| Liquid Biopsy beyond Cancer: A miRNA Detection in Serum with Electrochemical Chip for Non‐Invasive Coeliac Disease Diagnosis | 1-gen-2022 | Caratelli, Veronica; Moccia, Maria; Paggioro, Francesca R.; Fiore, Luca; Avitabile, Concetta; Saviano, Michele; Imbriani, Anna Lisa; Dardano, Principia; DE LUCA, Stefano; Moscone, Danila; Colabufo, Nicola A.; Ghafir El Idrissi, Imane; Russo, Francesco; Riezzo, Giuseppe; Giannelli, Gianluigi; Arduini, Fabiana | |
| Measurements of serum non-ceruloplasmin copper by a direct fluorescent methodspecific to Cu(II) | 1-gen-2017 | Squitti, R; Siotto, M; Cassetta, E; El Idrissi, Ig; Colabufo, Nicola Antonio | |
| Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures | 1-gen-2023 | Tylek, Kinga; Trojan, Ewa; Leśkiewicz, Monika; GHAFIR EL IDRISSI, Imane; Lacivita, Enza; Leopoldo, Marcello; Basta-Kaim, Agnieszka | |
| miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives | 1-gen-2014 | Gisel, Andreas; Valvano, Mirna; GHAFIR EL IDRISSI, Imane; Nardulli, Patrizia; Azzariti, Amalia; Carrieri, Antonio; Contino, Marialessandra; Colabufo, Nicola Antonio | |
| Miscele di caffè per la neuroprotezione | 1-gen-2016 | Colabufo, Na; Leopoldo, M; Berardi, F; Perrone, R; Cantore, M; Ghafir El Idrissi, I; Travaglio, D; Schino, I. | |
| Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey | 1-gen-2024 | Ghafir El Idrissi, I.; Santo, A.; Lacivita, E.; Leopoldo, M. | |
| Non-ceruplasmin copper didtincts subtypes in Alzheimer's disease: a genetic study of ATP7B frequency | 1-gen-2017 | Squitti, R; Ventriglia, M; Gennarelli, M; Colabufo, Nicola Antonio; Ghafir El Idrissi, I; Bucossi, S; Mariani, S; Rongioletti, M; Zanetti, O; Congiu, C; Rossini, Pm; Bonvicini, C. | |
| P-GP RADIOTRACER FOR IMAGING AS BIOMARKERS INVOLVED IN ONSET OF NEURODEGENERATIVE DISEASE | 1-gen-2015 | Ghafir El Idrissi, Imane; Cantore, Mariangela; Berardi, Francesco; Leopoldo, Marcello; Perrone, Roberto; Colabufo, Nicola Antonio | |
| RATIONAL DESIGN AND SYNTHESIS OF POTENTIAL SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT) RADIOLIGANDS FOR IN VIVO IMAGING OF P2X7 RECEPTORS | 1-gen-2022 | Ghafir El Idrissi, I.; Lacivita, E.; Dal, Ben; D., Volpini; R., Leopoldo | |
| Structure-Activity Relationships and Therapeutic Potential of Purinergic P2X7 Receptor Antagonists | 1-gen-2024 | GHAFIR EL IDRISSI, Imane; Podlewska, Sabina; Abate, Carmen; J Bojarski, Andrzej; Lacivita, Enza; Leopoldo, Marcello |