BARBANENTE, ALESSANDRA
BARBANENTE, ALESSANDRA
DIPARTIMENTO DI CHIMICA
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring
2019-01-01 Papadia, Paride; Gandin, Valentina; Barbanente, Alessandra; Ruello, Alessandro G.; Marzano, Cristina; Micoli, Katia; Hoeschele, James D.; Natile, Giovanni; Margiotta, Nicola
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand
2019-01-01 Barbanente, Alessandra; Gandin, Valentina; Ditaranto, Nicoletta; Marzano, Cristina; Hoeschele, James D.; Suranna, Gian Paolo; Papadia, Paride; Natile, Giovanni; Margiotta, Nicola
Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases
2023-01-01 Barbanente, Alessandra; Ditaranto, Nicoletta; Laghezza, Antonio; Tortorella, Paolo; Intini, Francesco P; Pacifico, Concetta; Natile, Giovanni; Margiotta, Nicola
Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells
2023-01-01 Kopecka, Joanna; Barbanente, Alessandra; Vitone, Daniele; Arnesano, Fabio; Margiotta, Nicola; Berchialla, Paola; Niso, Mauro; Riganti, Chiara; Abate, Carmen
Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin
2021-01-01 Papadia, Paride; Barbanente, Alessandra; Ditaranto, Nicoletta; Hoeschele, James D; Natile, Giovanni; Marzano, Cristina; Gandin, Valentina; Margiotta, Nicola
Flying toward a plastic-free world: Can Drosophila serve as a model organism to develop new strategies of plastic waste management?
2024-01-01 Pignataro, Eugenia; Pini, Francesco; Barbanente, Alessandra; Arnesano, Fabio; Palazzo, Antonio; Marsano, RENE' MASSIMILIANO
Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration
2022-01-01 Barbanente, Alessandra; Gandin, Valentina; Ceresa, Cecilia; Marzano, Cristina; Ditaranto, Nicoletta; Hoeschele, James D.; Natile, Giovanni; Arnesano, Fabio; Pacifico, Concetta; Intini, Francesco P.; Margiotta, Nicola
Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin
2022-01-01 Barbanente, A.; Galliani, A.; Iacobazzi, R. M.; Lasorsa, A.; Nardella, M. I.; Pennetta, A.; Margiotta, N.; Arnesano, F.
Molecular Dynamics and Structural Studies of Zinc Chloroquine Complexes
2023-01-01 Paulikat, Mirko; Vitone, Daniele; Schackert, Florian K; Schuth, Nils; Barbanente, Alessandra; Piccini, Giovannimaria; Ippoliti, Emiliano; Rossetti, Giulia; Clark, Adam H; Nachtegaal, Maarten; Haumann, Michael; Dau, Holger; Carloni, Paolo; Geremia, Silvano; De Zorzi, Rita; Quintanar, Liliana; Arnesano, Fabio
Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State
2022-01-01 Nardella, Maria Incoronata; Fortino, Mariagrazia; Barbanente, Alessandra; Natile, Giovanni; Pietropaolo, Adriana; Arnesano, Fabio
New Oxaliplatin-Pyrophosphato Analogs with Improved In Vitro Cytotoxicity
2021-01-01 Barbanente, Alessandra; Maria Iacobazzi, Rosa; Azzariti, Amalia; Hoeschele, James D.; Denora, Nunzio; Papadia, Paride; Pacifico, Concetta; Natile, Giovanni; Margiotta, Nicola
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond
2020-01-01 Barbanente, A.; Margiotta, N.; Pacifico, C.; Intini, F. P.; Natile, G.
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance
2020-01-01 Papadia, P.; Micoli, K.; Barbanente, A.; Ditaranto, N.; Hoeschele, J. D.; Natile, G.; Marzano, C.; Gandin, V.; Margiotta, N.
Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells
2020-01-01 Barbanente, A.; Nadar, R. A.; Esposti, L. D.; Palazzo, B.; Iafisco, M.; Van Den Beucken, J. J. J. P.; Leeuwenburgh, S. C. G.; Margiotta, N.
Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model
2020-01-01 Nadar, R. A.; Asokan, N.; Degli Esposti, L.; Curci, A.; Barbanente, A.; Schlatt, L.; Karst, U.; Iafisco, M.; Margiotta, N.; Brand, M.; Van Den Beucken, J. J. J. P.; Bornhauser, M.; Leeuwenburgh, S. C. G.
Pt(ii) and Pt(iv) complexes with a major component of royal jelly as innovative antitumor drug candidates
2023-01-01 Barbanente, Alessandra; Gandin, Valentina; Donati, Chiara; Pierro, CARMELA ILARIA; Natile, Giovanni; Margiotta, Nicola
Pt(II) complex containing the 1R,2R enantiomer of trans-1,2-diamino-4-cyclohexene ligand effectively and selectively inhibits the viability of aggressive pancreatic adenocarcinoma cells and alters their lipid metabolism
2022-01-01 Novohradsky, Vojtech; Markova, Lenka; Kostrhunova, Hana; Svitelova, Marie; Kasparkova, Jana; Barbanente, Alessandra; Papadia, Paride; Margiotta, Nicola; Hoeschele, James D.; Brabec, Viktor
Pt(IV) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity
2021-01-01 Gabano, Elisabetta; Rangone, Beatrice; Perin, Elena; Caron, Giulia; Ermondi, Giuseppe; Vallaro, Maura; Gandin, Valentina; Marzano, Cristina; Barbanente, Alessandra; Margiotta, Nicola; Ravera, Mauro
Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy
2021-01-01 Barbanente, A.; Palazzo, B.; Esposti, L. D.; Adamiano, A.; Iafisco, M.; Ditaranto, N.; Migoni, D.; Gervaso, F.; Nadar, R.; Ivanchenko, P.; Leeuwenburgh, S.; Margiotta, N.
The mechanism of antiproliferative activity of the oxaliplatin pyrophosphate derivative involves its binding to nuclear DNA in cancer cells
2023-01-01 Pracharova, J.; Kostrhunova, H.; Barbanente, A.; Margiotta, N.; Brabec, V.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring | 1-gen-2019 | Papadia, Paride; Gandin, Valentina; Barbanente, Alessandra; Ruello, Alessandro G.; Marzano, Cristina; Micoli, Katia; Hoeschele, James D.; Natile, Giovanni; Margiotta, Nicola | |
| A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand | 1-gen-2019 | Barbanente, Alessandra; Gandin, Valentina; Ditaranto, Nicoletta; Marzano, Cristina; Hoeschele, James D.; Suranna, Gian Paolo; Papadia, Paride; Natile, Giovanni; Margiotta, Nicola | |
| Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases | 1-gen-2023 | Barbanente, Alessandra; Ditaranto, Nicoletta; Laghezza, Antonio; Tortorella, Paolo; Intini, Francesco P; Pacifico, Concetta; Natile, Giovanni; Margiotta, Nicola | |
| Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells | 1-gen-2023 | Kopecka, Joanna; Barbanente, Alessandra; Vitone, Daniele; Arnesano, Fabio; Margiotta, Nicola; Berchialla, Paola; Niso, Mauro; Riganti, Chiara; Abate, Carmen | |
| Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin | 1-gen-2021 | Papadia, Paride; Barbanente, Alessandra; Ditaranto, Nicoletta; Hoeschele, James D; Natile, Giovanni; Marzano, Cristina; Gandin, Valentina; Margiotta, Nicola | |
| Flying toward a plastic-free world: Can Drosophila serve as a model organism to develop new strategies of plastic waste management? | 1-gen-2024 | Pignataro, Eugenia; Pini, Francesco; Barbanente, Alessandra; Arnesano, Fabio; Palazzo, Antonio; Marsano, RENE' MASSIMILIANO | |
| Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration | 1-gen-2022 | Barbanente, Alessandra; Gandin, Valentina; Ceresa, Cecilia; Marzano, Cristina; Ditaranto, Nicoletta; Hoeschele, James D.; Natile, Giovanni; Arnesano, Fabio; Pacifico, Concetta; Intini, Francesco P.; Margiotta, Nicola | |
| Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin | 1-gen-2022 | Barbanente, A.; Galliani, A.; Iacobazzi, R. M.; Lasorsa, A.; Nardella, M. I.; Pennetta, A.; Margiotta, N.; Arnesano, F. | |
| Molecular Dynamics and Structural Studies of Zinc Chloroquine Complexes | 1-gen-2023 | Paulikat, Mirko; Vitone, Daniele; Schackert, Florian K; Schuth, Nils; Barbanente, Alessandra; Piccini, Giovannimaria; Ippoliti, Emiliano; Rossetti, Giulia; Clark, Adam H; Nachtegaal, Maarten; Haumann, Michael; Dau, Holger; Carloni, Paolo; Geremia, Silvano; De Zorzi, Rita; Quintanar, Liliana; Arnesano, Fabio | |
| Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State | 1-gen-2022 | Nardella, Maria Incoronata; Fortino, Mariagrazia; Barbanente, Alessandra; Natile, Giovanni; Pietropaolo, Adriana; Arnesano, Fabio | |
| New Oxaliplatin-Pyrophosphato Analogs with Improved In Vitro Cytotoxicity | 1-gen-2021 | Barbanente, Alessandra; Maria Iacobazzi, Rosa; Azzariti, Amalia; Hoeschele, James D.; Denora, Nunzio; Papadia, Paride; Pacifico, Concetta; Natile, Giovanni; Margiotta, Nicola | |
| One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond | 1-gen-2020 | Barbanente, A.; Margiotta, N.; Pacifico, C.; Intini, F. P.; Natile, G. | |
| Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance | 1-gen-2020 | Papadia, P.; Micoli, K.; Barbanente, A.; Ditaranto, N.; Hoeschele, J. D.; Natile, G.; Marzano, C.; Gandin, V.; Margiotta, N. | |
| Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells | 1-gen-2020 | Barbanente, A.; Nadar, R. A.; Esposti, L. D.; Palazzo, B.; Iafisco, M.; Van Den Beucken, J. J. J. P.; Leeuwenburgh, S. C. G.; Margiotta, N. | |
| Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model | 1-gen-2020 | Nadar, R. A.; Asokan, N.; Degli Esposti, L.; Curci, A.; Barbanente, A.; Schlatt, L.; Karst, U.; Iafisco, M.; Margiotta, N.; Brand, M.; Van Den Beucken, J. J. J. P.; Bornhauser, M.; Leeuwenburgh, S. C. G. | |
| Pt(ii) and Pt(iv) complexes with a major component of royal jelly as innovative antitumor drug candidates | 1-gen-2023 | Barbanente, Alessandra; Gandin, Valentina; Donati, Chiara; Pierro, CARMELA ILARIA; Natile, Giovanni; Margiotta, Nicola | |
| Pt(II) complex containing the 1R,2R enantiomer of trans-1,2-diamino-4-cyclohexene ligand effectively and selectively inhibits the viability of aggressive pancreatic adenocarcinoma cells and alters their lipid metabolism | 1-gen-2022 | Novohradsky, Vojtech; Markova, Lenka; Kostrhunova, Hana; Svitelova, Marie; Kasparkova, Jana; Barbanente, Alessandra; Papadia, Paride; Margiotta, Nicola; Hoeschele, James D.; Brabec, Viktor | |
| Pt(IV) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity | 1-gen-2021 | Gabano, Elisabetta; Rangone, Beatrice; Perin, Elena; Caron, Giulia; Ermondi, Giuseppe; Vallaro, Maura; Gandin, Valentina; Marzano, Cristina; Barbanente, Alessandra; Margiotta, Nicola; Ravera, Mauro | |
| Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy | 1-gen-2021 | Barbanente, A.; Palazzo, B.; Esposti, L. D.; Adamiano, A.; Iafisco, M.; Ditaranto, N.; Migoni, D.; Gervaso, F.; Nadar, R.; Ivanchenko, P.; Leeuwenburgh, S.; Margiotta, N. | |
| The mechanism of antiproliferative activity of the oxaliplatin pyrophosphate derivative involves its binding to nuclear DNA in cancer cells | 1-gen-2023 | Pracharova, J.; Kostrhunova, H.; Barbanente, A.; Margiotta, N.; Brabec, V. |