LEONE, PIERO
LEONE, PIERO
DIPARTIMENTO DI BIOSCIENZE , BIOTECNOLOGIE E AMBIENTE
3D structure prediction and AFM morphology study of human FAD synthase (isoform 2).
2017-01-01 Seral, V. T.; Medina, M.; Leone, P.; Barile, M.; Lostao, A.; Martínez-Júlvez, M.
Alteration of flavin homeostasis in neuromuscular disorders and cancer
2019-01-01 Tolomeo, Maria; Leone, Piero; Barile, Maria
Bacterial production, characterization and protein modeling of a novel monofuctional isoform of FAD synthase in humans: an emergency protein?
2018-01-01 Leone, P.; Galluccio, M.; Barbiroli, A.; Eberini, I.; Tolomeo, M.; Vrenna, F.; Gianazza, E.; Iametti, S.; Bonomi, F.; Indiveri, C.; Barile, M.
Combined isobutyryl‐CoA and multiple acyl‐CoA dehydrogenase deficiency in a boy with altered riboflavin homeostasis
2022-01-01 Tummolo, Albina; Leone, Piero; Tolomeo, Maria; Solito, Rita; Mattiuzzo, Matteo; Lepri, Francesca Romana; Lorè, Tania; Cardinali, Roberta; De Giovanni, Donatella; Simonetti, Simonetta; Barile, Maria
Continuous and Discontinuous Approaches to Study FAD Synthesis and Degradation Catalyzed by Purified Recombinant FAD Synthase or Cellular Fractions
2021-01-01 Leone, Piero; Tolomeo, Maria; Barile, Maria
Development of Novel Experimental Models to Study Flavoproteome Alterations in Human Neuromuscular Diseases: The Effect of Rf Therapy
2020-01-01 Tolomeo, M.; Nisco, A.; Leone, P.; Barile, M.
FAD forming and destroying via human FAD synthase: a puzzle of modulated and modulating activities
2019-01-01 Leone, Piero; Quarta, Stefano; Galluccio, Michele; Indiveri, Cesare; Barile, Maria
FAD synthase (FADs) localization and function in neuronal cell model and worms: a possible involvement of FADs in the pathogenesis of neurodegenerative diseases.
2016-01-01 Difonzo, G.; Giancaspero, T. A.; Busco, G.; Leone, P.; Zampi, G.; Damiano, M. T.; Piancone, E.; Pica, R.; Puzzovio, P.; De Giorgi, C.; Di Schiavi, E.; Colella, M.; Barile, M.
FAD Synthase (FADS) localization and function in neuronal cell models: a possible involvement of FADS in the pathogenesis of neurodegenerative diseases.
2017-01-01 Difonzo, G.; Leone, P.; Tolomeo, M.; Defrancesco, M. L.; Damiano, M. T.; Giancaspero, T. A.; Colella, M.; Barile, M.
FAD synthase deficiency: a severe mitochondrial myopathy involving a secondary reduction of RFVT2 expression
2022-01-01 Barile, Maria; Tolomeo, Maria; Chimienti, Guglielmina; Lanza, Martina; Barbaro, Roberto; Latronico, Tiziana; Nisco, Alessia; Leone, Piero; Petrosillo, Giuseppe; Liuzzi, Grazia M.; Lezza, Angela M. S.; Colella, Matilde; Olsen, Rikke K.
FAD synthase deficiency: a severe mitochondrial myopathy searching for novel therapeutic strategies
2020-01-01 Barile, M.; Tolomeo, M.; Latronico, T.; Chimenti, G.; Leone, P.; Nisco, A.; Dipace, G.; Cardinale, M.; Lanza, M.; Barbaro, R.; Petrosillo, G.; Lezza, A. M. S.; Liuzzi, G. M.; Colella, M.; Olsen, R.
FAD SYNTHASE IN HUMAN MULTIPLE ACYL-COA DEHYDROGENASE DEFICIENCY: INVESTIGATIONS IN S. CEREVISIAE
2018-01-01 Leone, Piero; Tolomeo, Maria; Giancaspero, TERESA ANNA; Bruni, Francesco; Oreb, Mislav; Roberti, Marina; Boles, Eckhard; Barile, Maria
Flavin-sensitive variant FAD Synthases underlying riboflavin responsive Multiple Acyl-CoA Dehydrogenation Deficiency.
2016-01-01 Mosegaard, S.; Giancaspero, T. A.; Galluccio, M.; Leone, P.; Boneh, A.; Auranen, M.; Tyni, T.; Vergani, L.; Malena, A.; Pegoraro, E.; Botta, A.; Holzerová, E.; Prokish, H.; Gregersen, N.; Olsen, R. K. J.; Barile, M.
Functional characterization and homology modeling of a novel monofunctional isoform of human FAD synthase.
2017-01-01 Leone, P.; Galluccio, M.; Tolomeo, M.; Indiveri, C.; Barile, M.
hFADS6 and its “supermutant”: a possible therapeutic target?
2019-01-01 Leone, Piero; Quarta, S.; Galluccio, M.; Indiveri, C.; Barile, M.
Human FAD synthase is a bi-functional enzyme with a FAD hydrolase activity in the molybdopterin binding domain
2015-01-01 Giancaspero, TERESA ANNA; Galluccio, Michele; Miccolis, Angelica; Leone, Piero; Eberini, Ivano; Iametti, Stefania; Indiveri, Cesare; Barile, Maria
Increased demand for FAD synthesis in differentiated and stem pancreatic cancer cells is accomplished by modulating FLAD1 gene expression: the inhibitory effect of Chicago Sky Blue
2023-01-01 Nisco, Alessia; Carvalho, Tiago M A; Tolomeo, Maria; Di Molfetta, Daria; Leone, Piero; Galluccio, Michele; Medina, Milagros; Indiveri, Cesare; Reshkin, Stephan Joel; Cardone, Rosa Angela; Barile, Maria
Micronutrient Deficiency in Inherited Metabolic Disorders Requiring Diet Regimen: A Brief Critical Review
2023-01-01 Tummolo, Albina; Carella, Rosa; De Giovanni, Donatella; Paterno, Giulia; Simonetti, Simonetta; Tolomeo, Maria; Leone, Piero; Barile, Maria
Mimicking human riboflavin responsive neuromuscular disorders by silencing flad-1 gene in C. elegans: Alteration of vitamin transport and cholinergic transmission
2022-01-01 Leone, P.; Tolomeo, M.; Piancone, E.; Puzzovio, P. G.; De Giorgi, C.; Indiveri, C.; Di Schiavi, E.; Barile, M.
MODULATING CELLULAR FLAVIN COFACTOR LEVELS IN HUMANS VIA THE BI-FUNCTIONAL AND MONOFUNCTIONAL FLAD1 GENE PRODUCTS
2018-01-01 Barile, Maria; Leone, Piero; Tolomeo, Maria; Galluccio, Michele; Indiveri, Cesare
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3D structure prediction and AFM morphology study of human FAD synthase (isoform 2). | 1-gen-2017 | Seral, V. T.; Medina, M.; Leone, P.; Barile, M.; Lostao, A.; Martínez-Júlvez, M. | |
| Alteration of flavin homeostasis in neuromuscular disorders and cancer | 1-gen-2019 | Tolomeo, Maria; Leone, Piero; Barile, Maria | |
| Bacterial production, characterization and protein modeling of a novel monofuctional isoform of FAD synthase in humans: an emergency protein? | 1-gen-2018 | Leone, P.; Galluccio, M.; Barbiroli, A.; Eberini, I.; Tolomeo, M.; Vrenna, F.; Gianazza, E.; Iametti, S.; Bonomi, F.; Indiveri, C.; Barile, M. | |
| Combined isobutyryl‐CoA and multiple acyl‐CoA dehydrogenase deficiency in a boy with altered riboflavin homeostasis | 1-gen-2022 | Tummolo, Albina; Leone, Piero; Tolomeo, Maria; Solito, Rita; Mattiuzzo, Matteo; Lepri, Francesca Romana; Lorè, Tania; Cardinali, Roberta; De Giovanni, Donatella; Simonetti, Simonetta; Barile, Maria | |
| Continuous and Discontinuous Approaches to Study FAD Synthesis and Degradation Catalyzed by Purified Recombinant FAD Synthase or Cellular Fractions | 1-gen-2021 | Leone, Piero; Tolomeo, Maria; Barile, Maria | |
| Development of Novel Experimental Models to Study Flavoproteome Alterations in Human Neuromuscular Diseases: The Effect of Rf Therapy | 1-gen-2020 | Tolomeo, M.; Nisco, A.; Leone, P.; Barile, M. | |
| FAD forming and destroying via human FAD synthase: a puzzle of modulated and modulating activities | 1-gen-2019 | Leone, Piero; Quarta, Stefano; Galluccio, Michele; Indiveri, Cesare; Barile, Maria | |
| FAD synthase (FADs) localization and function in neuronal cell model and worms: a possible involvement of FADs in the pathogenesis of neurodegenerative diseases. | 1-gen-2016 | Difonzo, G.; Giancaspero, T. A.; Busco, G.; Leone, P.; Zampi, G.; Damiano, M. T.; Piancone, E.; Pica, R.; Puzzovio, P.; De Giorgi, C.; Di Schiavi, E.; Colella, M.; Barile, M. | |
| FAD Synthase (FADS) localization and function in neuronal cell models: a possible involvement of FADS in the pathogenesis of neurodegenerative diseases. | 1-gen-2017 | Difonzo, G.; Leone, P.; Tolomeo, M.; Defrancesco, M. L.; Damiano, M. T.; Giancaspero, T. A.; Colella, M.; Barile, M. | |
| FAD synthase deficiency: a severe mitochondrial myopathy involving a secondary reduction of RFVT2 expression | 1-gen-2022 | Barile, Maria; Tolomeo, Maria; Chimienti, Guglielmina; Lanza, Martina; Barbaro, Roberto; Latronico, Tiziana; Nisco, Alessia; Leone, Piero; Petrosillo, Giuseppe; Liuzzi, Grazia M.; Lezza, Angela M. S.; Colella, Matilde; Olsen, Rikke K. | |
| FAD synthase deficiency: a severe mitochondrial myopathy searching for novel therapeutic strategies | 1-gen-2020 | Barile, M.; Tolomeo, M.; Latronico, T.; Chimenti, G.; Leone, P.; Nisco, A.; Dipace, G.; Cardinale, M.; Lanza, M.; Barbaro, R.; Petrosillo, G.; Lezza, A. M. S.; Liuzzi, G. M.; Colella, M.; Olsen, R. | |
| FAD SYNTHASE IN HUMAN MULTIPLE ACYL-COA DEHYDROGENASE DEFICIENCY: INVESTIGATIONS IN S. CEREVISIAE | 1-gen-2018 | Leone, Piero; Tolomeo, Maria; Giancaspero, TERESA ANNA; Bruni, Francesco; Oreb, Mislav; Roberti, Marina; Boles, Eckhard; Barile, Maria | |
| Flavin-sensitive variant FAD Synthases underlying riboflavin responsive Multiple Acyl-CoA Dehydrogenation Deficiency. | 1-gen-2016 | Mosegaard, S.; Giancaspero, T. A.; Galluccio, M.; Leone, P.; Boneh, A.; Auranen, M.; Tyni, T.; Vergani, L.; Malena, A.; Pegoraro, E.; Botta, A.; Holzerová, E.; Prokish, H.; Gregersen, N.; Olsen, R. K. J.; Barile, M. | |
| Functional characterization and homology modeling of a novel monofunctional isoform of human FAD synthase. | 1-gen-2017 | Leone, P.; Galluccio, M.; Tolomeo, M.; Indiveri, C.; Barile, M. | |
| hFADS6 and its “supermutant”: a possible therapeutic target? | 1-gen-2019 | Leone, Piero; Quarta, S.; Galluccio, M.; Indiveri, C.; Barile, M. | |
| Human FAD synthase is a bi-functional enzyme with a FAD hydrolase activity in the molybdopterin binding domain | 1-gen-2015 | Giancaspero, TERESA ANNA; Galluccio, Michele; Miccolis, Angelica; Leone, Piero; Eberini, Ivano; Iametti, Stefania; Indiveri, Cesare; Barile, Maria | |
| Increased demand for FAD synthesis in differentiated and stem pancreatic cancer cells is accomplished by modulating FLAD1 gene expression: the inhibitory effect of Chicago Sky Blue | 1-gen-2023 | Nisco, Alessia; Carvalho, Tiago M A; Tolomeo, Maria; Di Molfetta, Daria; Leone, Piero; Galluccio, Michele; Medina, Milagros; Indiveri, Cesare; Reshkin, Stephan Joel; Cardone, Rosa Angela; Barile, Maria | |
| Micronutrient Deficiency in Inherited Metabolic Disorders Requiring Diet Regimen: A Brief Critical Review | 1-gen-2023 | Tummolo, Albina; Carella, Rosa; De Giovanni, Donatella; Paterno, Giulia; Simonetti, Simonetta; Tolomeo, Maria; Leone, Piero; Barile, Maria | |
| Mimicking human riboflavin responsive neuromuscular disorders by silencing flad-1 gene in C. elegans: Alteration of vitamin transport and cholinergic transmission | 1-gen-2022 | Leone, P.; Tolomeo, M.; Piancone, E.; Puzzovio, P. G.; De Giorgi, C.; Indiveri, C.; Di Schiavi, E.; Barile, M. | |
| MODULATING CELLULAR FLAVIN COFACTOR LEVELS IN HUMANS VIA THE BI-FUNCTIONAL AND MONOFUNCTIONAL FLAD1 GENE PRODUCTS | 1-gen-2018 | Barile, Maria; Leone, Piero; Tolomeo, Maria; Galluccio, Michele; Indiveri, Cesare |