Sfoglia per Autore
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations
2019-01-01 Zizzari, A.; Bianco, M.; Perrone, E.; Manera, M. G.; Cellamare, S.; Ferorelli, S.; Purgatorio, R.; Scilimati, A.; Tolomeo, A.; Dimiccoli, V.; Rella, R.; Arima, V.
Identification of chromeno[3,2-c]pyridine as suitable scaffold of novel multitarget-directed ligands for the treatment of Alzheimer’s disease.
2019-01-01 Purgatorio, R.; Catto, M.; Pisani, L.; de Candia, M.; Cellamare, S.; Kulikova, L. N.; Voskressensky, L. G.; Altomare, C. D.
Repositioning of dantrolene for Alzheimer’s disease: new and old biological activities towards AD-related targets.
2019-01-01 Catto, M.; Bolognino, I.; Giangregorio, N.; de Candia, M.; Pisani, L.; Purgatorio, R.; Rullo, M.; Altomare, C. D.; Cellamare, S.
Identification of chromeno[3,2-c]pyridine as suitable scaffold of novel multitarget-directed ligands for the treatment of Alzheimers disease
2019-01-01 Purgatorio, R.; Catto, M.; Pisani, L.; de Candia, M.; Cellamare, S.; Kulikova, L. N.; Voskressensky, L. G.; Altomare, C. D.
Pyrrolo[2,1-a]isoquinoline scaffold in drug discovery: Advances in synthesis and medicinal chemistry
2019-01-01 Matveeva, M. D.; Purgatorio, R.; Voskressensky, L. G.; Altomare, C. D.
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease
2019-01-01 Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M
Development of a continuous flow synthesis of propranolol: tackling a competitive side reaction
2019-01-01 De Angelis, S.; Celestini, P.; Purgatorio, R.; Degennaro, L.; Rebuzzini, G.; Luisi, R.; Carlucci, C.
Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease
2019-01-01 Purgatorio, R.; de Candia, M.; Catto, M.; Carrieri, A.; Pisani, L.; De Palma, A.; Toma, M.; Ivanova, O. A.; Voskressensky, L. G.; Altomare, C. D.
Reductive Domino Reaction to Access Chromeno [2, 3-c] isoquinoline-5-amines with Antiproliferative Activities Against Human Tumor Cells
2020-01-01 Yue, Xiaoyi; A Festa, Alexey; A Storozhenko, Olga; V Varlamov, Alexey; Subramani, Karthikeyan; Boccarelli, Angelina; Purgatorio, Rosa; Altomare, Cosimo Damiano; G Voskressensky, Leonid
Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multitarget Ligands Directed towards Relevant Alzheimer's Targets
2020-01-01 Purgatorio, R.; Kulikova, L. N.; Pisani, L.; Catto, M.; de Candia, M.; Carrieri, A.; Cellamare, S.; De Palma, A.; Beloglazkin, A. A.; Reza Raesi, G.; Voskressensky, L. G.; Altomare, C. D.
Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease
2020-01-01 Purgatorio, Rosa; Gambacorta, Nicola; Catto, Marco; de Candia, Modesto; Pisani, Leonardo; Espargaró, Alba; Sabaté, Raimon; Cellamare, Saverio; Nicolotti, Orazio; Altomare, Cosimo D
Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors
2021-01-01 Kobzev, M. S.; Titov, A. A.; Alexandrova, E. V.; Purgatorio, R.; Catto, M.; Sorokina, E. A.; Borisova, T. N.; Varlamov, A. V.; Altomare, C. D.; Voskressensky, L. G.
Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential
2021-01-01 Nevskaya, A. A.; Anikina, L. V.; Purgatorio, R.; Catto, M.; Nicolotti, O.; de Candia, M.; Pisani, L.; Borisova, T. N.; Miftyakhova, A. R.; Varlamov, A. V.; Nevskaya, E. Y.; Borisov, R. S.; Voskressensky, L. G.; Altomare, C. D.
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease.
2021-01-01 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease
2021-01-01 Purgatorio, Rosa; Gambacorta, Nicola; DE CANDIA, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Nicolotti, Orazio; Altomare, Cosimo Damiano
Evaluation of water‐soluble Mannich base prodrugs of 2,3,4,5‐tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as multitarget‐directed agents for Alzheimer’s disease
2021-01-01 Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Denora, Nunzio; Carrieri, Antonio; Nevskaya, Alisa A.; Voskressensky, Leonid G.; Altomare, Cosimo D.
Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase
2022-01-01 Bolognino, Isabella; Carrieri, Antonio; Purgatorio, Rosa; Catto, Marco; Caliandro, Rocco; Carrozzini, Benedetta; Belviso, BENNY DANILO; Majellaro, Maria; Sotelo, Eddy; Cellamare, Saverio; Altomare, Cosimo Damiano
The pivotal role of pyrrolidine ring as multitarget scaffold in neurodegenerative diseases
2022-01-01 Carrieri, A.; Barbarossa, A.; de Candia, M.; Purgatorio, R.; Brunetti, L.; Piemontese, L.; Limongelli, F.; Lentini, G.; Carocci, A.
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease
2022-01-01 Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga
Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity
2022-01-01 Titov, Alexander A.; Purgatorio, Rosa; Obydennik, Arina Y.; Listratova, Anna V.; Borisova, Tatiana N.; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo D.; Varlamov, Alexey V.; Voskressensky, Leonid G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Microfluidic pervaporation of ethanol from radiopharmaceutical formulations | 1-gen-2019 | Zizzari, A.; Bianco, M.; Perrone, E.; Manera, M. G.; Cellamare, S.; Ferorelli, S.; Purgatorio, R.; Scilimati, A.; Tolomeo, A.; Dimiccoli, V.; Rella, R.; Arima, V. | |
| Identification of chromeno[3,2-c]pyridine as suitable scaffold of novel multitarget-directed ligands for the treatment of Alzheimer’s disease. | 1-gen-2019 | Purgatorio, R.; Catto, M.; Pisani, L.; de Candia, M.; Cellamare, S.; Kulikova, L. N.; Voskressensky, L. G.; Altomare, C. D. | |
| Repositioning of dantrolene for Alzheimer’s disease: new and old biological activities towards AD-related targets. | 1-gen-2019 | Catto, M.; Bolognino, I.; Giangregorio, N.; de Candia, M.; Pisani, L.; Purgatorio, R.; Rullo, M.; Altomare, C. D.; Cellamare, S. | |
| Identification of chromeno[3,2-c]pyridine as suitable scaffold of novel multitarget-directed ligands for the treatment of Alzheimers disease | 1-gen-2019 | Purgatorio, R.; Catto, M.; Pisani, L.; de Candia, M.; Cellamare, S.; Kulikova, L. N.; Voskressensky, L. G.; Altomare, C. D. | |
| Pyrrolo[2,1-a]isoquinoline scaffold in drug discovery: Advances in synthesis and medicinal chemistry | 1-gen-2019 | Matveeva, M. D.; Purgatorio, R.; Voskressensky, L. G.; Altomare, C. D. | |
| A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease | 1-gen-2019 | Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M | |
| Development of a continuous flow synthesis of propranolol: tackling a competitive side reaction | 1-gen-2019 | De Angelis, S.; Celestini, P.; Purgatorio, R.; Degennaro, L.; Rebuzzini, G.; Luisi, R.; Carlucci, C. | |
| Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease | 1-gen-2019 | Purgatorio, R.; de Candia, M.; Catto, M.; Carrieri, A.; Pisani, L.; De Palma, A.; Toma, M.; Ivanova, O. A.; Voskressensky, L. G.; Altomare, C. D. | |
| Reductive Domino Reaction to Access Chromeno [2, 3-c] isoquinoline-5-amines with Antiproliferative Activities Against Human Tumor Cells | 1-gen-2020 | Yue, Xiaoyi; A Festa, Alexey; A Storozhenko, Olga; V Varlamov, Alexey; Subramani, Karthikeyan; Boccarelli, Angelina; Purgatorio, Rosa; Altomare, Cosimo Damiano; G Voskressensky, Leonid | |
| Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multitarget Ligands Directed towards Relevant Alzheimer's Targets | 1-gen-2020 | Purgatorio, R.; Kulikova, L. N.; Pisani, L.; Catto, M.; de Candia, M.; Carrieri, A.; Cellamare, S.; De Palma, A.; Beloglazkin, A. A.; Reza Raesi, G.; Voskressensky, L. G.; Altomare, C. D. | |
| Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease | 1-gen-2020 | Purgatorio, Rosa; Gambacorta, Nicola; Catto, Marco; de Candia, Modesto; Pisani, Leonardo; Espargaró, Alba; Sabaté, Raimon; Cellamare, Saverio; Nicolotti, Orazio; Altomare, Cosimo D | |
| Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors | 1-gen-2021 | Kobzev, M. S.; Titov, A. A.; Alexandrova, E. V.; Purgatorio, R.; Catto, M.; Sorokina, E. A.; Borisova, T. N.; Varlamov, A. V.; Altomare, C. D.; Voskressensky, L. G. | |
| Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential | 1-gen-2021 | Nevskaya, A. A.; Anikina, L. V.; Purgatorio, R.; Catto, M.; Nicolotti, O.; de Candia, M.; Pisani, L.; Borisova, T. N.; Miftyakhova, A. R.; Varlamov, A. V.; Nevskaya, E. Y.; Borisov, R. S.; Voskressensky, L. G.; Altomare, C. D. | |
| 3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. | 1-gen-2021 | Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D. | |
| First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease | 1-gen-2021 | Purgatorio, Rosa; Gambacorta, Nicola; DE CANDIA, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Nicolotti, Orazio; Altomare, Cosimo Damiano | |
| Evaluation of water‐soluble Mannich base prodrugs of 2,3,4,5‐tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as multitarget‐directed agents for Alzheimer’s disease | 1-gen-2021 | Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Denora, Nunzio; Carrieri, Antonio; Nevskaya, Alisa A.; Voskressensky, Leonid G.; Altomare, Cosimo D. | |
| Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase | 1-gen-2022 | Bolognino, Isabella; Carrieri, Antonio; Purgatorio, Rosa; Catto, Marco; Caliandro, Rocco; Carrozzini, Benedetta; Belviso, BENNY DANILO; Majellaro, Maria; Sotelo, Eddy; Cellamare, Saverio; Altomare, Cosimo Damiano | |
| The pivotal role of pyrrolidine ring as multitarget scaffold in neurodegenerative diseases | 1-gen-2022 | Carrieri, A.; Barbarossa, A.; de Candia, M.; Purgatorio, R.; Brunetti, L.; Piemontese, L.; Limongelli, F.; Lentini, G.; Carocci, A. | |
| 1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease | 1-gen-2022 | Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga | |
| Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity | 1-gen-2022 | Titov, Alexander A.; Purgatorio, Rosa; Obydennik, Arina Y.; Listratova, Anna V.; Borisova, Tatiana N.; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo D.; Varlamov, Alexey V.; Voskressensky, Leonid G. |
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