LEUCI, ROSALBA
LEUCI, ROSALBA
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
2- Aryloxymethylene-substituted scaffolds as privileged moieties for the design of new potential metal chelators in the multi-target therapy of Alzheimer's disease
2024-01-01 Leuci, Rosalba; Paparella, Marco; Chaves, Silvia; Carrieri, Antonio; Laghezza, Antonio; Cerini, Marco; Loiodice, Fulvio; Tortorella, Paolo; Amelia Santos, M.; Piemontese, Luca
3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate
2024-01-01 Leuci, Rosalba; Dininno, Daniela; Paparella, Marco; Piemontese, Luca
A Chemical Modification of a Peroxisome Proliferator-Activated Receptor Pan Agonist Produced a Shift to a New Dual Alpha/Gamma Partial Agonist Endowed with Mitochondrial Pyruvate Carrier Inhibition and Antidiabetic Properties
2024-01-01 Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Montanari, Roberta; Capelli, Davide; Wackerlig, Judith; Simic, Stefan; Falbo, Emanuele; Pecora, Lucia; Leuci, Rosalba; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Singh, Ravi Pratap; Tambe, Suhas; Sudeep, C. A.; Pattnaik, Ashok Kumar; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity
2022-01-01 Sblano, S.; Cerchia, C.; Laghezza, A.; Piemontese, L.; Brunetti, L.; Leuci, R.; Gilardi, F.; Thomas, A.; Genovese, M.; Santi, A.; Tortorella, P.; Paoli, P.; Lavecchia, A.; Loiodice, F.
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION
2023-01-01 Cerchia, C.; Laghezza, A.; Genovese, M.; Leuci, R.; Pranzini, E.; Santi, A.; Brunetti, L.; Piemontese, L.; Tortorella, P.; Biswas, A.; Singh, R. P.; Tambe, S.; Ca, S.; Pattnaik, A. K.; Jayaprakash, V.; Paoli, P.; Loiodice, F.; Lavecchia, A.
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition
2023-01-01 Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Leuci, Rosalba; Pranzini, Erica; Santi, Alice; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Pratap Singh, Ravi; Tambe, Suhas; Ca, Sudeep; Kumar Pattnaik, Ashok; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio
A new potent and selective peroxisome proliferator-activated receptor alpha partial agonist displays anti-steatotic effects In vitro and behaves as a safe hypolipidemic and hypoglycemic agent in a diabetic mouse model
2025-01-01 Laghezza, A.; Falbo, E.; Gilardi, F.; Thomas, A.; Brunetti, L.; Leuci, R.; Piemontese, L.; Tortorella, P.; Biswas, A.; Singh, R. P.; Pattnaik, A. K.; Jayaprakash, V.; Tambe, S.; Ca, S.; Wackerlig-Damle, J.; Paoli, P.; Loiodice, F.; Lavecchia, A.
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)
2022-01-01 Leuci, R.; Brunetti, L.; Laghezza, A.; Piemontese, L.; Carrieri, A.; Pisani, L.; Tortorella, P.; Catto, M.; Loiodice, F.
A new series of rivastigmine structure-based hybrids for a multi-target approach to Alzheimer’s disease
2023-01-01 Leuci, Rosalba
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders
2020-01-01 Leuci, Rosalba; Brunetti, Leonardo; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio; Piemontese, Luca
Can foods influence the onset and progress of neurodegenerative diseases?
2022-01-01 Piemontese, Luca; Brunetti, Leonardo; Leuci, Rosalba
Deep Eutectic Solvents (DESs) as Alternative Sustainable Media for the Extraction and Characterization of Bioactive Compounds from Winemaking Industry Wastes
2025-01-01 Roselli, Vincenzo; Leuci, Rosalba; Pugliese, Gianluca; Barbarossa, Alexia; Laghezza, Antonio; Paparella, Marco; Carocci, Alessia; Tufarelli, Vincenzo; Gambacorta, Lucia; Piemontese, Luca
Deep Eutectic Solvents as Convenient Media for the Preparation of Semi-synthetic Anti-AD Multi-Target Hybrids
2025-01-01 Leuci, Rosalba; Paparella, Marco; Carrieri, Antonio; Roselli, Vincenzo; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo; Carocci, Alessia; Ferrara, Massimo; Magistà, Donato; Gallo, Antonia; Gialluisi, Katia; Gambacorta, Lucia; Perrone, Giancarlo; Piemontese, Luca
Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding
2022-01-01 Brunetti, Leonardo; Leuci, Rosalba; Colonna, Maria Antonietta; Carrieri, Rossana; Celentano, Francesco Emanuele; Bozzo, Giancarlo; Loiodice, Fulvio; Selvaggi, Maria; Tufarelli, Vincenzo; Piemontese, Luca
From classical MTDLs to a semi-synthetic innovative green approach: nature-inspired design as a new intriguing opportunity for new anti-Alzheimer’s drugs
2024-01-01 Leuci, Rosalba; Carrieri, Antonio; Wackerlig, Judith; Chaves, Silvia; Catto, Marco; Laghezza, Antonio; Brunetti, Leonardo; LA SPADA, Gabriella; Loiodice, Fulvio; Tortorella, Paolo; Carocci, Alessia; Simic, Stefan; Amelia Santos, Maria; Gambacorta, Lucia; Gallo, Antonia; Perrone, Giancarlo; Piemontese, Luca
Grape pomace as a valuable source of nutraceuticals in Deep Eutectic Solvents ready-to-use extracts
2025-01-01 Roselli, Vincenzo; Leuci, Rosalba; Paparella, Marco; Pugliese, Gianluca; Barbarossa, Alexia; Carocci, Alessia; Manyes, Lara; Laghezza, Antonio; Tufarelli, Vincenzo; Meca, Giuseppe; Gambacorta, Lucia; Piemontese, Luca
Green methods for the recovery of bioactive molecules from natural sources
2025-01-01 Paparella, Marco; Leuci, Rosalba; Roselli, Vincenzo; Gialluisi, Katia; Laghezza, Antonio; Ferrara, Massimo; Perrone, Giancarlo; Gambacorta, Lucia; Piemontese, Luca
Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy
2024-01-01 Roselli, Vincenzo; Pugliese, Gianluca; Leuci, Rosalba; Brunetti, Leonardo; Gambacorta, Lucia; Tufarelli, Vincenzo; Piemontese, Luca
Green solvents as an alternative, sustainable practice for the recovery of phenolic compounds in grape pomace
2024-01-01 Roselli, Vincenzo; Gambacorta, Lucia; Leuci, Rosalba; Laghezza, Antonio; Tufarelli, Vincenzo; Pugliese, Gianluca; Piemontese, Luca
IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ
2023-01-01 Laghezza, A.; Brunetti, L.; Leuci, R.; Tortorella, P.; Piemontese, L.; Paoli, P.; Jayaprakash, V.; Cerchia, C.; Lavecchia, A.; Loiodice, F.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2- Aryloxymethylene-substituted scaffolds as privileged moieties for the design of new potential metal chelators in the multi-target therapy of Alzheimer's disease | 1-gen-2024 | Leuci, Rosalba; Paparella, Marco; Chaves, Silvia; Carrieri, Antonio; Laghezza, Antonio; Cerini, Marco; Loiodice, Fulvio; Tortorella, Paolo; Amelia Santos, M.; Piemontese, Luca | |
| 3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate | 1-gen-2024 | Leuci, Rosalba; Dininno, Daniela; Paparella, Marco; Piemontese, Luca | |
| A Chemical Modification of a Peroxisome Proliferator-Activated Receptor Pan Agonist Produced a Shift to a New Dual Alpha/Gamma Partial Agonist Endowed with Mitochondrial Pyruvate Carrier Inhibition and Antidiabetic Properties | 1-gen-2024 | Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Montanari, Roberta; Capelli, Davide; Wackerlig, Judith; Simic, Stefan; Falbo, Emanuele; Pecora, Lucia; Leuci, Rosalba; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Singh, Ravi Pratap; Tambe, Suhas; Sudeep, C. A.; Pattnaik, Ashok Kumar; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio | |
| A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity | 1-gen-2022 | Sblano, S.; Cerchia, C.; Laghezza, A.; Piemontese, L.; Brunetti, L.; Leuci, R.; Gilardi, F.; Thomas, A.; Genovese, M.; Santi, A.; Tortorella, P.; Paoli, P.; Lavecchia, A.; Loiodice, F. | |
| A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION | 1-gen-2023 | Cerchia, C.; Laghezza, A.; Genovese, M.; Leuci, R.; Pranzini, E.; Santi, A.; Brunetti, L.; Piemontese, L.; Tortorella, P.; Biswas, A.; Singh, R. P.; Tambe, S.; Ca, S.; Pattnaik, A. K.; Jayaprakash, V.; Paoli, P.; Loiodice, F.; Lavecchia, A. | |
| A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition | 1-gen-2023 | Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Leuci, Rosalba; Pranzini, Erica; Santi, Alice; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Pratap Singh, Ravi; Tambe, Suhas; Ca, Sudeep; Kumar Pattnaik, Ashok; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio | |
| A new potent and selective peroxisome proliferator-activated receptor alpha partial agonist displays anti-steatotic effects In vitro and behaves as a safe hypolipidemic and hypoglycemic agent in a diabetic mouse model | 1-gen-2025 | Laghezza, A.; Falbo, E.; Gilardi, F.; Thomas, A.; Brunetti, L.; Leuci, R.; Piemontese, L.; Tortorella, P.; Biswas, A.; Singh, R. P.; Pattnaik, A. K.; Jayaprakash, V.; Tambe, S.; Ca, S.; Wackerlig-Damle, J.; Paoli, P.; Loiodice, F.; Lavecchia, A. | |
| A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) | 1-gen-2022 | Leuci, R.; Brunetti, L.; Laghezza, A.; Piemontese, L.; Carrieri, A.; Pisani, L.; Tortorella, P.; Catto, M.; Loiodice, F. | |
| A new series of rivastigmine structure-based hybrids for a multi-target approach to Alzheimer’s disease | 1-gen-2023 | Leuci, Rosalba | |
| A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders | 1-gen-2020 | Leuci, Rosalba; Brunetti, Leonardo; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio; Piemontese, Luca | |
| Can foods influence the onset and progress of neurodegenerative diseases? | 1-gen-2022 | Piemontese, Luca; Brunetti, Leonardo; Leuci, Rosalba | |
| Deep Eutectic Solvents (DESs) as Alternative Sustainable Media for the Extraction and Characterization of Bioactive Compounds from Winemaking Industry Wastes | 1-gen-2025 | Roselli, Vincenzo; Leuci, Rosalba; Pugliese, Gianluca; Barbarossa, Alexia; Laghezza, Antonio; Paparella, Marco; Carocci, Alessia; Tufarelli, Vincenzo; Gambacorta, Lucia; Piemontese, Luca | |
| Deep Eutectic Solvents as Convenient Media for the Preparation of Semi-synthetic Anti-AD Multi-Target Hybrids | 1-gen-2025 | Leuci, Rosalba; Paparella, Marco; Carrieri, Antonio; Roselli, Vincenzo; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo; Carocci, Alessia; Ferrara, Massimo; Magistà, Donato; Gallo, Antonia; Gialluisi, Katia; Gambacorta, Lucia; Perrone, Giancarlo; Piemontese, Luca | |
| Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding | 1-gen-2022 | Brunetti, Leonardo; Leuci, Rosalba; Colonna, Maria Antonietta; Carrieri, Rossana; Celentano, Francesco Emanuele; Bozzo, Giancarlo; Loiodice, Fulvio; Selvaggi, Maria; Tufarelli, Vincenzo; Piemontese, Luca | |
| From classical MTDLs to a semi-synthetic innovative green approach: nature-inspired design as a new intriguing opportunity for new anti-Alzheimer’s drugs | 1-gen-2024 | Leuci, Rosalba; Carrieri, Antonio; Wackerlig, Judith; Chaves, Silvia; Catto, Marco; Laghezza, Antonio; Brunetti, Leonardo; LA SPADA, Gabriella; Loiodice, Fulvio; Tortorella, Paolo; Carocci, Alessia; Simic, Stefan; Amelia Santos, Maria; Gambacorta, Lucia; Gallo, Antonia; Perrone, Giancarlo; Piemontese, Luca | |
| Grape pomace as a valuable source of nutraceuticals in Deep Eutectic Solvents ready-to-use extracts | 1-gen-2025 | Roselli, Vincenzo; Leuci, Rosalba; Paparella, Marco; Pugliese, Gianluca; Barbarossa, Alexia; Carocci, Alessia; Manyes, Lara; Laghezza, Antonio; Tufarelli, Vincenzo; Meca, Giuseppe; Gambacorta, Lucia; Piemontese, Luca | |
| Green methods for the recovery of bioactive molecules from natural sources | 1-gen-2025 | Paparella, Marco; Leuci, Rosalba; Roselli, Vincenzo; Gialluisi, Katia; Laghezza, Antonio; Ferrara, Massimo; Perrone, Giancarlo; Gambacorta, Lucia; Piemontese, Luca | |
| Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy | 1-gen-2024 | Roselli, Vincenzo; Pugliese, Gianluca; Leuci, Rosalba; Brunetti, Leonardo; Gambacorta, Lucia; Tufarelli, Vincenzo; Piemontese, Luca | |
| Green solvents as an alternative, sustainable practice for the recovery of phenolic compounds in grape pomace | 1-gen-2024 | Roselli, Vincenzo; Gambacorta, Lucia; Leuci, Rosalba; Laghezza, Antonio; Tufarelli, Vincenzo; Pugliese, Gianluca; Piemontese, Luca | |
| IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ | 1-gen-2023 | Laghezza, A.; Brunetti, L.; Leuci, R.; Tortorella, P.; Piemontese, L.; Paoli, P.; Jayaprakash, V.; Cerchia, C.; Lavecchia, A.; Loiodice, F. |