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LEUCI, ROSALBA

LEUCI, ROSALBA  

DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO  

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3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate 1-gen-2024 Leuci, Rosalba; Dininno, Daniela; Paparella, Marco; Piemontese, Luca
A Chemical Modification of a Peroxisome Proliferator-Activated Receptor Pan Agonist Produced a Shift to a New Dual Alpha/Gamma Partial Agonist Endowed with Mitochondrial Pyruvate Carrier Inhibition and Antidiabetic Properties 1-gen-2024 Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Montanari, Roberta; Capelli, Davide; Wackerlig, Judith; Simic, Stefan; Falbo, Emanuele; Pecora, Lucia; Leuci, Rosalba; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Singh, Ravi Pratap; Tambe, Suhas; Sudeep, C. A.; Pattnaik, Ashok Kumar; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 1-gen-2022 Sblano, S.; Cerchia, C.; Laghezza, A.; Piemontese, L.; Brunetti, L.; Leuci, R.; Gilardi, F.; Thomas, A.; Genovese, M.; Santi, A.; Tortorella, P.; Paoli, P.; Lavecchia, A.; Loiodice, F.
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION 1-gen-2023 Cerchia, C.; Laghezza, A.; Genovese, M.; Leuci, R.; Pranzini, E.; Santi, A.; Brunetti, L.; Piemontese, L.; Tortorella, P.; Biswas, A.; Singh, R. P.; Tambe, S.; Ca, S.; Pattnaik, A. K.; Jayaprakash, V.; Paoli, P.; Loiodice, F.; Lavecchia, A.
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 1-gen-2023 Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Leuci, Rosalba; Pranzini, Erica; Santi, Alice; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Pratap Singh, Ravi; Tambe, Suhas; Ca, Sudeep; Kumar Pattnaik, Ashok; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 1-gen-2022 Leuci, R.; Brunetti, L.; Laghezza, A.; Piemontese, L.; Carrieri, A.; Pisani, L.; Tortorella, P.; Catto, M.; Loiodice, F.
A new series of rivastigmine structure-based hybrids for a multi-target approach to Alzheimer’s disease 1-gen-2023 Leuci, Rosalba
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 1-gen-2020 Leuci, Rosalba; Brunetti, Leonardo; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio; Piemontese, Luca
Can foods influence the onset and progress of neurodegenerative diseases? 1-gen-2022 Piemontese, Luca; Brunetti, Leonardo; Leuci, Rosalba
Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding 1-gen-2022 Brunetti, Leonardo; Leuci, Rosalba; Colonna, Maria Antonietta; Carrieri, Rossana; Celentano, Francesco Emanuele; Bozzo, Giancarlo; Loiodice, Fulvio; Selvaggi, Maria; Tufarelli, Vincenzo; Piemontese, Luca
From classical MTDLs to a semi-synthetic innovative green approach: nature-inspired design as a new intriguing opportunity for new anti-Alzheimer’s drugs 1-gen-2024 Leuci, Rosalba; Carrieri, Antonio; Wackerlig, Judith; Chaves, Silvia; Catto, Marco; Laghezza, Antonio; Brunetti, Leonardo; LA SPADA, Gabriella; Loiodice, Fulvio; Tortorella, Paolo; Carocci, Alessia; Simic, Stefan; Amelia Santos, Maria; Gambacorta, Lucia; Gallo, Antonia; Perrone, Giancarlo; Piemontese, Luca
Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy 1-gen-2024 Roselli, Vincenzo; Pugliese, Gianluca; Leuci, Rosalba; Brunetti, Leonardo; Gambacorta, Lucia; Tufarelli, Vincenzo; Piemontese, Luca
IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ 1-gen-2023 Laghezza, A.; Brunetti, L.; Leuci, R.; Tortorella, P.; Piemontese, L.; Paoli, P.; Jayaprakash, V.; Cerchia, C.; Lavecchia, A.; Loiodice, F.
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 1-gen-2020 Leuci, Rosalba; Brunetti, Leonardo; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo; Piemontese, Luca
Multi-Target Approach for the Design of New Compounds Potentially Useful for the Prevention and Treatment of Cardiovascular and/or Neurodegenerative Diseases 1-gen-2021 Leuci, R.; Brunetti, L.; Carocci, A.; Carrieri, A.; Catto, M.; Laghezza, A.; Tortorella, P.; Piemontese, L.; Loiodice, F.
Multi-target approach for the treatment of chronic and degenerative diseases 1-gen-2021 Leuci, R.
Multiple causes, multiple targets: FAAH as a centerpiece for therapy of multifactorial pathologies. 1-gen-2021 Brunetti, Leonardo; Leuci, Rosalba; Carrieri, Antonio; Laghezza, Antonio; Catto, Marco; Piemontese, Luca; Tortorella, Paolo; Loiodice, Fulvio
N-(2-(Benzylamino)ethyl)-4-(naphthalene-1-sulfonamido)benzamide 1-gen-2024 Leuci, Rosalba; Loiodice, Fulvio; Piemontese, Luca
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases 1-gen-2021 Leuci, Rosalba; Brunetti, Leonardo; Poliseno, Viviana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo; Piemontese, Luca
Nature-inspired structures for the multi-target treatment of Alzheimer’s disease: a successful approach for drug design 1-gen-2022 Leuci, Rosalba; Poliseno, Viviana; Solfrizzo, Michele; Santos M., Amélia; Chaves, Sílvia; Laghezza, Antonio; Catto, Marco; Carrieri, Antonio; Loiodice, Fulvio; Piemontese, Luca