SAMARELLI, FRANCESCO
SAMARELLI, FRANCESCO
Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
2022-01-01 Purgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; DE CANDIA, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D.
Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults
2024-01-01 Samarelli, Francesco; Purgatorio, Rosa; Lopopolo, Gianfranco; Deruvo, Caterina; Catto, Marco; Andresini, Michael; Carrieri, Antonio; Nicolotti, Orazio; DE PALMA, Annalisa; Miniero, DANIELA VALERIA; DE CANDIA, Modesto; Altomare, Cosimo D.
Radiosynthesis and whole-body distribution in mice of a 18 F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease
2023-01-01 Lee, Sang Hee; Purgatorio, Rosa; Samarelli, Francesco; Catto, Marco; Denora, Nunzio; Morgese, Maria Grazia; Tucci, Paolo; Trabace, Luigia; Kim, Hye Won; Park, Hyun Soo; Kim, Sang Eun; Lee, Byung Chul; de Candia, Modesto; Altomare, Cosimo D
Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease
2023-01-01 Czarnota-Łydka, Kinga; Sudoł-Tałaj, Sylwia; Kucwaj-Brysz, Katarzyna; Kurczab, Rafał; Satała, Grzegorz; de Candia, Modesto; Samarelli, Francesco; Altomare, Cosimo Damiano; Carocci, Alessia; Barbarossa, Alexia; Żesławska, Ewa; Głuch-Lutwin, Monika; Mordyl, Barbara; Kubacka, Monika; Wilczyńska-Zawal, Natalia; Jastrzębska-Więsek, Magdalena; Partyka, Anna; Khan, Nadia; Więcek, Małgorzata; Nitek, Wojciech; Honkisz-Orzechowska, Ewelina; Latacz, Gniewomir; Wesołowska, Anna; Carrieri, Antonio; Handzlik, Jadwiga
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases | 1-gen-2022 | Purgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; DE CANDIA, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D. | |
| Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults | 1-gen-2024 | Samarelli, Francesco; Purgatorio, Rosa; Lopopolo, Gianfranco; Deruvo, Caterina; Catto, Marco; Andresini, Michael; Carrieri, Antonio; Nicolotti, Orazio; DE PALMA, Annalisa; Miniero, DANIELA VALERIA; DE CANDIA, Modesto; Altomare, Cosimo D. | |
| Radiosynthesis and whole-body distribution in mice of a 18 F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease | 1-gen-2023 | Lee, Sang Hee; Purgatorio, Rosa; Samarelli, Francesco; Catto, Marco; Denora, Nunzio; Morgese, Maria Grazia; Tucci, Paolo; Trabace, Luigia; Kim, Hye Won; Park, Hyun Soo; Kim, Sang Eun; Lee, Byung Chul; de Candia, Modesto; Altomare, Cosimo D | |
| Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease | 1-gen-2023 | Czarnota-Łydka, Kinga; Sudoł-Tałaj, Sylwia; Kucwaj-Brysz, Katarzyna; Kurczab, Rafał; Satała, Grzegorz; de Candia, Modesto; Samarelli, Francesco; Altomare, Cosimo Damiano; Carocci, Alessia; Barbarossa, Alexia; Żesławska, Ewa; Głuch-Lutwin, Monika; Mordyl, Barbara; Kubacka, Monika; Wilczyńska-Zawal, Natalia; Jastrzębska-Więsek, Magdalena; Partyka, Anna; Khan, Nadia; Więcek, Małgorzata; Nitek, Wojciech; Honkisz-Orzechowska, Ewelina; Latacz, Gniewomir; Wesołowska, Anna; Carrieri, Antonio; Handzlik, Jadwiga |