SANESE, PAOLA
SANESE, PAOLA
A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth
2015-01-01 Peserico, Alessia; Germani, Aldo; Sanese, Paola; Barbosa, Armenio Jorge; Di Virgilio, Valeria; Fittipaldi, Raffaella; Fabini, Edoardo; Bertucci, Carlo; Varchi, Greta; Moyer, Mary Pat; Caretti, Giuseppina; Del Rio, Alberto; Simone, Cristiano
c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer
2022-01-01 Lepore Signorile, Martina; Grossi, Valentina; Fasano, Candida; Forte, Giovanna; Disciglio, Vittoria; Sanese, Paola; De Marco, Katia; La Rocca, Francesca; Armentano, Raffaele; Valentini, Anna Maria; Giannelli, Gianluigi; Simone, Cristiano
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype
2022-01-01 Mancarella, S.; Serino, G.; Gigante, I.; Cigliano, A.; Ribback, S.; Sanese, P.; Grossi, V.; Simone, C.; Armentano, R.; Evert, M.; Calvisi, D. F.; Giannelli, G.
Chasing the Foxo3: Insights into its new mitochondrial lair in colorectal cancer landscape
2019-01-01 Grossi, V.; Fasano, C.; Celestini, V.; Signorile, M. L.; Sanese, P.; Simone, C.
Classic Galactosemia: Clinical and Computational Characterization of a Novel GALT Missense Variant (p.A303D) and a Literature Review
2023-01-01 Forte, Giovanna; Buonadonna, Antonia Lucia; Pantaleo, Antonino; Fasano, Candida; Capodiferro, Donatella; Grossi, Valentina; Sanese, Paola; Cariola, Filomena; De Marco, Katia; Lepore Signorile, Martina; Manghisi, Andrea; Guglielmi, Anna Filomena; Simonetti, Simonetta; Laforgia, Nicola; Disciglio, Vittoria; Simone, Cristiano
Clinical and Molecular Characterization of SMAD4 Splicing Variants in Patients with Juvenile Polyposis Syndrome
2024-01-01 Forte, Giovanna; Buonadonna, Antonia Lucia; Fasano, Candida; Sanese, Paola; Cariola, Filomena; Manghisi, Andrea; Guglielmi, Anna Filomena; Lepore Signorile, Martina; De Marco, Katia; Grossi, Valentina; Disciglio, Vittoria; Simone, Cristiano
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes
2023-01-01 Forte, Giovanna; Cariola, Filomena; Buonadonna, Antonia Lucia; Guglielmi, Anna Filomena; Manghisi, Andrea; De Marco, Katia; Grossi, Valentina; Fasano, Candida; Lepore Signorile, Martina; Sanese, Paola; Bagnulo, Rosanna; Resta, Nicoletta; Disciglio, Vittoria; Simone, Cristiano
Discovery of an allosteric ligand binding site in SMYD3 lysine methyltransferase
2021-01-01 Talibov, Vladimir O; Fabini, Edoardo; Fitzgerald, Edward; Tedesco, Daniele; Eriksson, Daniela; Talu, Martin J; Rachman, Moira M; Mihalic, Filip; Manoni, Elisabetta; Naldi, Marina; Sanese, Paola; Forte, Giovanna; Signorile, Martina Lepore; Barril, Xavier; Simone, Cristiano; Bartolini, Manuela; Dobritzsch, Doreen; Del Rio, Alberto; Danielson, U Helena
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3
2022-01-01 Parenti, Marco Daniele; Naldi, Marina; Manoni, Elisabetta; Fabini, Edoardo; Cederfelt, Daniela; Talibov, Vladimir O; Gressani, Valeria; Guven, Ummu; Grossi, Valentina; Fasano, Candida; Sanese, Paola; De Marco, Katia; Shtil, Alexander A; Kurkin, Alexander V; Altieri, Andrea; Danielson, U Helena; Caretti, Giuseppina; Simone, Cristiano; Varchi, Greta; Bartolini, Manuela; Del Rio, Alberto
Exploring the Relationship of rs2802292 with Diabetes and NAFLD in a Southern Italian Cohort-Nutrihep Study
2024-01-01 Forte, Giovanna; Donghia, Rossella; Lepore Signorile, Martina; Tatoli, Rossella; Bonfiglio, Caterina; Losito, Francesco; De Marco, Katia; Manghisi, Andrea; Guglielmi, Filomena Anna; Disciglio, Vittoria; Fasano, Candida; Sanese, Paola; Cariola, Filomena; Buonadonna, Antonia Lucia; Grossi, Valentina; Giannelli, Gianluigi; Simone, Cristiano
FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs
2019-01-01 Sanese, P.; Forte, G.; Disciglio, V.; Grossi, V.; Simone, C.
Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3′-end
2019-01-01 Disciglio, V.; Fasano, C.; Cariola, F.; Forte, G.; Grossi, Valentina; Sanese, P.; Lepore Signorile, M.; Resta, N.; Lotesoriere, C.; Stella, A.; Lolli, I.; Simone, C.
Histone and DNA Methylation as Epigenetic Regulators of DNA Damage Repair in Gastric Cancer and Emerging Therapeutic Opportunities
2023-01-01 De Marco, Katia; Sanese, Paola; Simone, Cristiano; Grossi, Valentina
Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors
2022-01-01 Disciglio, Vittoria; Sanese, Paola; Fasano, Candida; Lotesoriere, Claudio; Valentini, Anna Maria; Forte, Giovanna; Lepore Signorile, Martina; De Marco, Katia; Grossi, Valentina; Lolli, Ivan; Cariola, Filomena; Simone, Cristiano
Identification of a novel germline APC N-terminal pathogenic variant associated with attenuated familial adenomatous polyposis
2024-01-01 Forte, Giovanna; Grossi, Valentina; Cariola, Filomena; Buonadonna, Antonia Lucia; Sanese, Paola; De Marco, Katia; Fasano, Candida; Lepore Signorile, Martina; Disciglio, Vittoria; Simone, Cristiano
Identifying novel SMYD3 interactors on the trail of cancer hallmarks
2022-01-01 Fasano, Candida; Lepore Signorile, Martina; De Marco, Katia; Forte, Giovanna; Sanese, Paola; Grossi, Valentina; Simone, Cristiano
In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes
2024-01-01 Fasano, Candida; Lepore Signorile, Martina; De Marco, Katia; Forte, Giovanna; Disciglio, Vittoria; Sanese, Paola; Grossi, Valentina; Simone, Cristiano
In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS)
2018-01-01 Ranieri, C; Di Tommaso, S; Loconte, D C; Grossi, V; Sanese, P; Bagnulo, R; Susca, F C; Forte, G; Peserico, A; De Luisi, A; Bartuli, A; Selicorni, A; Melis, D; Lerone, M; Praticò, A D; Abbadessa, G; Yu, Y; Schwartz, B; Ruggieri, Martino; Simone, Cristiano; Resta, Nicoletta
Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma
2018-01-01 Lucarelli, Giuseppe; Rutigliano, Monica; Sallustio, Fabio; Ribatti, Domenico; Giglio, Andrea; Lepore Signorile, Martina; Grossi, Valentina; Sanese, Paola; Napoli, Anna; Maiorano, Eugenio; Bianchi, Cristina; Perego, Roberto A; Ferro, Matteo; Ranieri, Elena; Serino, Grazia; Bell, Lauren N; Ditonno, Pasquale; Simone, Cristiano; Battaglia, Michele
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids
2021-01-01 Lepore Signorile, Martina; Grossi, Valentina; Di Franco, Simone; Forte, Giovanna; Disciglio, Vittoria; Fasano, Candida; Sanese, Paola; De Marco, Katia; Susca, Francesco Claudio; Mangiapane, Laura Rosa; Nicotra, Annalisa; Di Carlo, Gabriella; Dituri, Francesco; Giannelli, Gianluigi; Ingravallo, Giuseppe; Canettieri, Gianluca; Stassi, Giorgio; Simone, Cristiano
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth | 1-gen-2015 | Peserico, Alessia; Germani, Aldo; Sanese, Paola; Barbosa, Armenio Jorge; Di Virgilio, Valeria; Fittipaldi, Raffaella; Fabini, Edoardo; Bertucci, Carlo; Varchi, Greta; Moyer, Mary Pat; Caretti, Giuseppina; Del Rio, Alberto; Simone, Cristiano | |
| c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer | 1-gen-2022 | Lepore Signorile, Martina; Grossi, Valentina; Fasano, Candida; Forte, Giovanna; Disciglio, Vittoria; Sanese, Paola; De Marco, Katia; La Rocca, Francesca; Armentano, Raffaele; Valentini, Anna Maria; Giannelli, Gianluigi; Simone, Cristiano | |
| CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype | 1-gen-2022 | Mancarella, S.; Serino, G.; Gigante, I.; Cigliano, A.; Ribback, S.; Sanese, P.; Grossi, V.; Simone, C.; Armentano, R.; Evert, M.; Calvisi, D. F.; Giannelli, G. | |
| Chasing the Foxo3: Insights into its new mitochondrial lair in colorectal cancer landscape | 1-gen-2019 | Grossi, V.; Fasano, C.; Celestini, V.; Signorile, M. L.; Sanese, P.; Simone, C. | |
| Classic Galactosemia: Clinical and Computational Characterization of a Novel GALT Missense Variant (p.A303D) and a Literature Review | 1-gen-2023 | Forte, Giovanna; Buonadonna, Antonia Lucia; Pantaleo, Antonino; Fasano, Candida; Capodiferro, Donatella; Grossi, Valentina; Sanese, Paola; Cariola, Filomena; De Marco, Katia; Lepore Signorile, Martina; Manghisi, Andrea; Guglielmi, Anna Filomena; Simonetti, Simonetta; Laforgia, Nicola; Disciglio, Vittoria; Simone, Cristiano | |
| Clinical and Molecular Characterization of SMAD4 Splicing Variants in Patients with Juvenile Polyposis Syndrome | 1-gen-2024 | Forte, Giovanna; Buonadonna, Antonia Lucia; Fasano, Candida; Sanese, Paola; Cariola, Filomena; Manghisi, Andrea; Guglielmi, Anna Filomena; Lepore Signorile, Martina; De Marco, Katia; Grossi, Valentina; Disciglio, Vittoria; Simone, Cristiano | |
| Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes | 1-gen-2023 | Forte, Giovanna; Cariola, Filomena; Buonadonna, Antonia Lucia; Guglielmi, Anna Filomena; Manghisi, Andrea; De Marco, Katia; Grossi, Valentina; Fasano, Candida; Lepore Signorile, Martina; Sanese, Paola; Bagnulo, Rosanna; Resta, Nicoletta; Disciglio, Vittoria; Simone, Cristiano | |
| Discovery of an allosteric ligand binding site in SMYD3 lysine methyltransferase | 1-gen-2021 | Talibov, Vladimir O; Fabini, Edoardo; Fitzgerald, Edward; Tedesco, Daniele; Eriksson, Daniela; Talu, Martin J; Rachman, Moira M; Mihalic, Filip; Manoni, Elisabetta; Naldi, Marina; Sanese, Paola; Forte, Giovanna; Signorile, Martina Lepore; Barril, Xavier; Simone, Cristiano; Bartolini, Manuela; Dobritzsch, Doreen; Del Rio, Alberto; Danielson, U Helena | |
| Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3 | 1-gen-2022 | Parenti, Marco Daniele; Naldi, Marina; Manoni, Elisabetta; Fabini, Edoardo; Cederfelt, Daniela; Talibov, Vladimir O; Gressani, Valeria; Guven, Ummu; Grossi, Valentina; Fasano, Candida; Sanese, Paola; De Marco, Katia; Shtil, Alexander A; Kurkin, Alexander V; Altieri, Andrea; Danielson, U Helena; Caretti, Giuseppina; Simone, Cristiano; Varchi, Greta; Bartolini, Manuela; Del Rio, Alberto | |
| Exploring the Relationship of rs2802292 with Diabetes and NAFLD in a Southern Italian Cohort-Nutrihep Study | 1-gen-2024 | Forte, Giovanna; Donghia, Rossella; Lepore Signorile, Martina; Tatoli, Rossella; Bonfiglio, Caterina; Losito, Francesco; De Marco, Katia; Manghisi, Andrea; Guglielmi, Filomena Anna; Disciglio, Vittoria; Fasano, Candida; Sanese, Paola; Cariola, Filomena; Buonadonna, Antonia Lucia; Grossi, Valentina; Giannelli, Gianluigi; Simone, Cristiano | |
| FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs | 1-gen-2019 | Sanese, P.; Forte, G.; Disciglio, V.; Grossi, V.; Simone, C. | |
| Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3′-end | 1-gen-2019 | Disciglio, V.; Fasano, C.; Cariola, F.; Forte, G.; Grossi, Valentina; Sanese, P.; Lepore Signorile, M.; Resta, N.; Lotesoriere, C.; Stella, A.; Lolli, I.; Simone, C. | |
| Histone and DNA Methylation as Epigenetic Regulators of DNA Damage Repair in Gastric Cancer and Emerging Therapeutic Opportunities | 1-gen-2023 | De Marco, Katia; Sanese, Paola; Simone, Cristiano; Grossi, Valentina | |
| Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors | 1-gen-2022 | Disciglio, Vittoria; Sanese, Paola; Fasano, Candida; Lotesoriere, Claudio; Valentini, Anna Maria; Forte, Giovanna; Lepore Signorile, Martina; De Marco, Katia; Grossi, Valentina; Lolli, Ivan; Cariola, Filomena; Simone, Cristiano | |
| Identification of a novel germline APC N-terminal pathogenic variant associated with attenuated familial adenomatous polyposis | 1-gen-2024 | Forte, Giovanna; Grossi, Valentina; Cariola, Filomena; Buonadonna, Antonia Lucia; Sanese, Paola; De Marco, Katia; Fasano, Candida; Lepore Signorile, Martina; Disciglio, Vittoria; Simone, Cristiano | |
| Identifying novel SMYD3 interactors on the trail of cancer hallmarks | 1-gen-2022 | Fasano, Candida; Lepore Signorile, Martina; De Marco, Katia; Forte, Giovanna; Sanese, Paola; Grossi, Valentina; Simone, Cristiano | |
| In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes | 1-gen-2024 | Fasano, Candida; Lepore Signorile, Martina; De Marco, Katia; Forte, Giovanna; Disciglio, Vittoria; Sanese, Paola; Grossi, Valentina; Simone, Cristiano | |
| In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS) | 1-gen-2018 | Ranieri, C; Di Tommaso, S; Loconte, D C; Grossi, V; Sanese, P; Bagnulo, R; Susca, F C; Forte, G; Peserico, A; De Luisi, A; Bartuli, A; Selicorni, A; Melis, D; Lerone, M; Praticò, A D; Abbadessa, G; Yu, Y; Schwartz, B; Ruggieri, Martino; Simone, Cristiano; Resta, Nicoletta | |
| Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma | 1-gen-2018 | Lucarelli, Giuseppe; Rutigliano, Monica; Sallustio, Fabio; Ribatti, Domenico; Giglio, Andrea; Lepore Signorile, Martina; Grossi, Valentina; Sanese, Paola; Napoli, Anna; Maiorano, Eugenio; Bianchi, Cristina; Perego, Roberto A; Ferro, Matteo; Ranieri, Elena; Serino, Grazia; Bell, Lauren N; Ditonno, Pasquale; Simone, Cristiano; Battaglia, Michele | |
| Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids | 1-gen-2021 | Lepore Signorile, Martina; Grossi, Valentina; Di Franco, Simone; Forte, Giovanna; Disciglio, Vittoria; Fasano, Candida; Sanese, Paola; De Marco, Katia; Susca, Francesco Claudio; Mangiapane, Laura Rosa; Nicotra, Annalisa; Di Carlo, Gabriella; Dituri, Francesco; Giannelli, Gianluigi; Ingravallo, Giuseppe; Canettieri, Gianluca; Stassi, Giorgio; Simone, Cristiano |