Sfoglia per Autore
Stereospecific synthesis of “para-hydroxymexiletine“ amd sodium channel blocking activity evaluation
2004-01-01 Catalano, A.; Carocci, A.; Fracchiolla, G.; Franchini, C.; Tortorella, V.; De Luca, A.; De Bellis, M.; Desaphy, J. F.; Conte Camerino, D.
Stereospecific Synthesis of ‘‘para-Hydroxymexiletine’’ and Sodium Channel Blocking Activity Evaluation
2004-01-01 Catalano, Alessia; Carocci, Alessia; Fracchiolla, Giuseppe; Carlo, Franchini; Lentini, Giovanni; Vincenzo, Tortorella; DE LUCA, Annamaria; DE BELLIS, Michela; Desaphy, Jean Francois; DIANA CONTE CAMERINO,
Pharmacological activity of major metabolites of mexiletine on skeletal muscle sodium currents
2005-01-01 DE BELLIS, Michela; DE LUCA, A; Catalano, Alessia; Carocci, Alessia; Lentini, Giovanni; Franchini, C; Tortorella, V; CONTE CAMERINO, D.
Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents
2006-01-01 DE BELLIS, Michela; DE LUCA, Annamaria; Rana, F; Cavalluzzi, MARIA MADDALENA; Catalano, Alessia; Lentini, Giovanni; Franchini, Carlo; Tortorella, V; Conte, Diana
Molecular spatial geometry of CLC-K ligands: optimal requirements towards high affinity channel block
2007-01-01 Liantonio, Antonella; Conte, Diana; Babini, E; DE BELLIS, Michela; Fracchiolla, Giuseppe; Carbonara, Giuseppe Gerardo; Loiodice, Fulvio; Tortorella, Paolo; Pusch, M; Conte, D.
Molecular spatial geometry of CLC-K ligands: optimal requirements towards high affinity channel block
2007-01-01 Liantonio, Antonella; Conte, Diana; Babini, E; DE BELLIS, Michela; Fracchiolla, Giuseppe; Carbonara, Giuseppe Gerardo; Loiodice, Fulvio; Tortorella, Paolo; Pusch, M; Conte, Diana; Alessandra, Picollo
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers
2007-01-01 Muraglia, M; Franchini, C; Corbo, F; Scilimati, A; Sinicropi, Ms; DE LUCA, A; DE BELLIS, M; Conte, D; Tortorella, V.
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle
2008-01-01 DE LUCA, Annamaria; Nico, Beatrice; Rolland, Jf; Cozzoli, A; Burdi, R; Mangieri, D; Giannuzzi, V; Liantonio, Antonella; Cippone, V; DE BELLIS, Michela; Nicchia, GRAZIA PAOLA; Frigeri, Antonio; Svelto, Maria; Conte, Diana; Camerino, GIULIA MARIA
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents
2008-01-01 Catalano, Alessia; Carocci, Alessia; Corbo, Filomena Faustina Rina; Franchini, Carlo; Muraglia, M; Scilimati, Antonio; DE BELLIS, Michela; DE LUCA, Annamaria; Conte, Diana; Sinicropi, Ms; Tortorella, Vincenzo
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor
2009-01-01 Desaphy, Jean Francois; Dipalma, A.; Costanza, T.; DE BELLIS, Michela; George, A. L. J. r.; Conte, Diana
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents
2009-01-01 Carocci, Alessia; Bruno, C; Catalano, Alessia; Lentini, Giovanni; Franchini, Carlo; DE BELLIS, Michela; DE LUCA, A; CONTE CAMERINO, D.
Newly synthesized mexiletine and tocainide analogues are potent use-dependent blockers of skeletal muscle sodium channels: potential implication for antimyotonic activity
2009-01-01 DE BELLIS, Michela; De Luca, A; Lentini, Giovanni; Carocci, Alessia; Corbo, F; Franchini, C; Conte, Diana
Large screening of newly synthesized Mexiletine and Tocanide analogs as potent use-dependent blockers of skeletal muscle sodium channels: identification of the structural requirements for improving antimyotonic activity
2009-01-01 DE BELLIS, Michela; DE LUCA, A; Lentini, Giovanni; Carocci, Alessia; Corbo, F; Franchini, C; CONTE CAMERINO, D.
LARGE SCREENING OF NEWLY SYNTHESIZED MEXILETINE AND TOCANIDE ANALOGS AS POTENT USE-DEPENDENT BLOCKERS OF SKELETAL MUSCLE SODIUM CHANNELS: IDENTIFICATION OF THE STRUCTURAL REQUIREMENTS FOR IMPROVING ANTIMYOTONIC ACTIVITY
2009-01-01 DE BELLIS, Michela; DE LUCA, A; Lentini, G; Carocci, Alessia; Corbo, Filomena Faustina Rina; Franchini, C; AND CONTE CAMERINO, D.
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine
2009-01-01 Desaphy, J-F; DI PALMA, A; DE BELLIS, M; Costanza, T; Gaudioso, C; Delmas, P; George, AL. JR; CONTE CAMERINO, D
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs
2010-01-01 Carocci, Alessia; Catalano, Alessia; Bruno, C; Lentini, Giovanni; Franchini, Carlo; DE BELLIS, Michela; DE LUCA, Annamaria; Conte, Diana
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels
2010-01-01 Zifarelli, G; Liantonio, Antonella; Gradogna, A; Conte, Diana; Gramegna, G; DE BELLIS, Michela; Murgia, A. R.; Babini, E; CONTE CAMERINO, D; Pusch, M.
Antitumorali
2011-01-01 Conte, Diana; DE LUCA, Annamaria; De Bellis, M.
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders
2011-01-01 DE BELLIS, Michela; Sblendorio, V.; Carocci, Alessia; Cavalluzzi, MARIA MADDALENA; Lentini, Giovanni; Franchini, C.; De Luca, A.; Conte, Diana
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders
2011-01-01 DE BELLIS, Michela; Sblendorio, V; Carocci, Alessia; Cavalluzzi, MARIA MADDALENA; Lentini, Giovanni; Franchini, C; DE LUCA, Annamaria; CONTE CAMERINO, D.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Stereospecific synthesis of “para-hydroxymexiletine“ amd sodium channel blocking activity evaluation | 1-gen-2004 | Catalano, A.; Carocci, A.; Fracchiolla, G.; Franchini, C.; Tortorella, V.; De Luca, A.; De Bellis, M.; Desaphy, J. F.; Conte Camerino, D. | |
Stereospecific Synthesis of ‘‘para-Hydroxymexiletine’’ and Sodium Channel Blocking Activity Evaluation | 1-gen-2004 | Catalano, Alessia; Carocci, Alessia; Fracchiolla, Giuseppe; Carlo, Franchini; Lentini, Giovanni; Vincenzo, Tortorella; DE LUCA, Annamaria; DE BELLIS, Michela; Desaphy, Jean Francois; DIANA CONTE CAMERINO, | |
Pharmacological activity of major metabolites of mexiletine on skeletal muscle sodium currents | 1-gen-2005 | DE BELLIS, Michela; DE LUCA, A; Catalano, Alessia; Carocci, Alessia; Lentini, Giovanni; Franchini, C; Tortorella, V; CONTE CAMERINO, D. | |
Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents | 1-gen-2006 | DE BELLIS, Michela; DE LUCA, Annamaria; Rana, F; Cavalluzzi, MARIA MADDALENA; Catalano, Alessia; Lentini, Giovanni; Franchini, Carlo; Tortorella, V; Conte, Diana | |
Molecular spatial geometry of CLC-K ligands: optimal requirements towards high affinity channel block | 1-gen-2007 | Liantonio, Antonella; Conte, Diana; Babini, E; DE BELLIS, Michela; Fracchiolla, Giuseppe; Carbonara, Giuseppe Gerardo; Loiodice, Fulvio; Tortorella, Paolo; Pusch, M; Conte, D. | |
Molecular spatial geometry of CLC-K ligands: optimal requirements towards high affinity channel block | 1-gen-2007 | Liantonio, Antonella; Conte, Diana; Babini, E; DE BELLIS, Michela; Fracchiolla, Giuseppe; Carbonara, Giuseppe Gerardo; Loiodice, Fulvio; Tortorella, Paolo; Pusch, M; Conte, Diana; Alessandra, Picollo | |
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers | 1-gen-2007 | Muraglia, M; Franchini, C; Corbo, F; Scilimati, A; Sinicropi, Ms; DE LUCA, A; DE BELLIS, M; Conte, D; Tortorella, V. | |
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle | 1-gen-2008 | DE LUCA, Annamaria; Nico, Beatrice; Rolland, Jf; Cozzoli, A; Burdi, R; Mangieri, D; Giannuzzi, V; Liantonio, Antonella; Cippone, V; DE BELLIS, Michela; Nicchia, GRAZIA PAOLA; Frigeri, Antonio; Svelto, Maria; Conte, Diana; Camerino, GIULIA MARIA | |
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents | 1-gen-2008 | Catalano, Alessia; Carocci, Alessia; Corbo, Filomena Faustina Rina; Franchini, Carlo; Muraglia, M; Scilimati, Antonio; DE BELLIS, Michela; DE LUCA, Annamaria; Conte, Diana; Sinicropi, Ms; Tortorella, Vincenzo | |
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor | 1-gen-2009 | Desaphy, Jean Francois; Dipalma, A.; Costanza, T.; DE BELLIS, Michela; George, A. L. J. r.; Conte, Diana | |
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents | 1-gen-2009 | Carocci, Alessia; Bruno, C; Catalano, Alessia; Lentini, Giovanni; Franchini, Carlo; DE BELLIS, Michela; DE LUCA, A; CONTE CAMERINO, D. | |
Newly synthesized mexiletine and tocainide analogues are potent use-dependent blockers of skeletal muscle sodium channels: potential implication for antimyotonic activity | 1-gen-2009 | DE BELLIS, Michela; De Luca, A; Lentini, Giovanni; Carocci, Alessia; Corbo, F; Franchini, C; Conte, Diana | |
Large screening of newly synthesized Mexiletine and Tocanide analogs as potent use-dependent blockers of skeletal muscle sodium channels: identification of the structural requirements for improving antimyotonic activity | 1-gen-2009 | DE BELLIS, Michela; DE LUCA, A; Lentini, Giovanni; Carocci, Alessia; Corbo, F; Franchini, C; CONTE CAMERINO, D. | |
LARGE SCREENING OF NEWLY SYNTHESIZED MEXILETINE AND TOCANIDE ANALOGS AS POTENT USE-DEPENDENT BLOCKERS OF SKELETAL MUSCLE SODIUM CHANNELS: IDENTIFICATION OF THE STRUCTURAL REQUIREMENTS FOR IMPROVING ANTIMYOTONIC ACTIVITY | 1-gen-2009 | DE BELLIS, Michela; DE LUCA, A; Lentini, G; Carocci, Alessia; Corbo, Filomena Faustina Rina; Franchini, C; AND CONTE CAMERINO, D. | |
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine | 1-gen-2009 | Desaphy, J-F; DI PALMA, A; DE BELLIS, M; Costanza, T; Gaudioso, C; Delmas, P; George, AL. JR; CONTE CAMERINO, D | |
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs | 1-gen-2010 | Carocci, Alessia; Catalano, Alessia; Bruno, C; Lentini, Giovanni; Franchini, Carlo; DE BELLIS, Michela; DE LUCA, Annamaria; Conte, Diana | |
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels | 1-gen-2010 | Zifarelli, G; Liantonio, Antonella; Gradogna, A; Conte, Diana; Gramegna, G; DE BELLIS, Michela; Murgia, A. R.; Babini, E; CONTE CAMERINO, D; Pusch, M. | |
Antitumorali | 1-gen-2011 | Conte, Diana; DE LUCA, Annamaria; De Bellis, M. | |
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders | 1-gen-2011 | DE BELLIS, Michela; Sblendorio, V.; Carocci, Alessia; Cavalluzzi, MARIA MADDALENA; Lentini, Giovanni; Franchini, C.; De Luca, A.; Conte, Diana | |
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders | 1-gen-2011 | DE BELLIS, Michela; Sblendorio, V; Carocci, Alessia; Cavalluzzi, MARIA MADDALENA; Lentini, Giovanni; Franchini, C; DE LUCA, Annamaria; CONTE CAMERINO, D. |
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