Sfoglia per Autore
5-HT and DA receptor affinity of arylpiperazine derivatives with terminal benzamide fragment
1994-01-01 Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, V.; Lograno, Marcello Diego; Daniele, E.; Govoni, S.
Mixed 5-HT1A/D-2 activity of a new model of arylpiperazines: 1-aryl-4-[3-(1,2-dihydronaphthalen-4-yl)-n-propyl]piperazines. 1. Synthesis and structure-activity relationships
1994-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S.
Conformationally restricted thiazole derivatives as novel class of 5-HT3 receptor ligands
1995-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Tortorella, V; Lograno, Md; Daniele, E; Govoni, S.
5-HT1A and D-2 receptor affinity of o-methoxyphenyl derivatives with terminal benzamide fragment on N-4 alkyl chain. 2
1995-01-01 Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, V; Lograno, Marcello Diego; Daniele, E; Govoni, S.
PREPARATION OF 1-(HETERO)ARYL-4-(CONDENSED THIAZOL-2-YLALKYL)PIPERAZINEDERIVATIVES FOR TREATMENT OF 5-HT1A- RECEPTOR MEDIATED DISORDERS
1995-01-01 Mc, Arthur; Perrone, Roberto; Fornaretto, M.
High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[(1-tetralin)alkyl]piperazines. 2
1995-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V.; Fiorentini, F.; Olgiati, V.; Ghiglieri, A.; Govoni, S.
1-Aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3
1996-01-01 Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, V; Fornaretto, Mg; Caccia, C; Mcarthur, Ra
Novel potent sigma-1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives
1996-01-01 Berardi, Francesco; Giudice, G.; Perrone, Roberto; Tortorella, V.; Govoni, S.; Lucchi, L.
New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives
1996-01-01 Berardi, Francesco; Colabufo, Nicola Antonio; Giudice, G.; Perrone, Roberto; Tortorella, V.; Govoni, S.; Lucchi, L.
Structure-activity relationship studies on 5-HT1A receptor affinity of 1-phenyl-4-[(alpha- or beta- tetralinyl)-alkyl]piperazines. 4
1996-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V; Fornaretto, Mg; Caccia, C; Mcarthur, Ra
1-(2-Methoxyphenyl)-4-alkylpiperazines: effect of the N-4 substituent on the affinity and selectivity for dopamine D4 receptor
1997-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V.
5-HT3 and 5-HT4 receptor affinities of naphtho[1,2-d]thiazole derivatives with various basic side chains
1997-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V.
Synthesis of arylpiperazines with a terminal naphthothiazole group and their evaluation on 5-HT, DA and alpha receptors
1997-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, N. A. A.; Tortorella, V.; Fornaretto, M.; Caccia, C.; Mcarthur, R. A.
4-[omega-Tetralin-1-yl]-1-benzylpiperazines and related compounds as 5-HT1A/D-2 ligands
1997-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Lograno, M.; Tortorella, V.
N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand
1998-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella,
N-omega-(Tetralin-1-yl)alkyl Derivatives of 3,3-Dimethylpiperidine Are Highly Potent and Selective sigma-1 or sigma-2 Ligands
1998-01-01 Berardi, Francesco; Santoro, S.; Perrone, Roberto; Tortorella, V.; Govoni, S.; Lucchi, L.
1-Aryl-4-[N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5
1999-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V.
Preparation of Carbon-11 labelled N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a radioligand with picomolar affinity for dopamine D4 receptors.
1999-01-01 Langer, O; Halldin, C; Chou, Y; Sandell, J; Swahn, C; Nagren, K; Perrone, R; Berardi, Francesco; Leopoldo, Marcello; Farde, L.
2-(Aryloxy)ethylamine derivatives: ring opened congeners of long chain 1-arylpiperazines with high 5-HT1A receptor affinity and selectivity versus D2 and a1 receptors
1999-01-01 Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V.
Le applicazioni della chimica farmaceutica
2000-01-01 Altomare, Cosimo Damiano; Berardi, Francesco; Carotti, Angelo; Casini, G; Catalano, Alessia; Ferappi, M; Franchini, C; Lentini, Giovanni; Liso, G; Loiodice, Fulvio; Perrone, R; Tangari, N; Tortorella, Paolo; Trapani, G; revisore TORTORELLA, V.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
5-HT and DA receptor affinity of arylpiperazine derivatives with terminal benzamide fragment | 1-gen-1994 | Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, V.; Lograno, Marcello Diego; Daniele, E.; Govoni, S. | |
Mixed 5-HT1A/D-2 activity of a new model of arylpiperazines: 1-aryl-4-[3-(1,2-dihydronaphthalen-4-yl)-n-propyl]piperazines. 1. Synthesis and structure-activity relationships | 1-gen-1994 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S. | |
Conformationally restricted thiazole derivatives as novel class of 5-HT3 receptor ligands | 1-gen-1995 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Tortorella, V; Lograno, Md; Daniele, E; Govoni, S. | |
5-HT1A and D-2 receptor affinity of o-methoxyphenyl derivatives with terminal benzamide fragment on N-4 alkyl chain. 2 | 1-gen-1995 | Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, V; Lograno, Marcello Diego; Daniele, E; Govoni, S. | |
PREPARATION OF 1-(HETERO)ARYL-4-(CONDENSED THIAZOL-2-YLALKYL)PIPERAZINEDERIVATIVES FOR TREATMENT OF 5-HT1A- RECEPTOR MEDIATED DISORDERS | 1-gen-1995 | Mc, Arthur; Perrone, Roberto; Fornaretto, M. | |
High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[(1-tetralin)alkyl]piperazines. 2 | 1-gen-1995 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V.; Fiorentini, F.; Olgiati, V.; Ghiglieri, A.; Govoni, S. | |
1-Aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3 | 1-gen-1996 | Perrone, Roberto; Berardi, Francesco; Leopoldo, Marcello; Tortorella, V; Fornaretto, Mg; Caccia, C; Mcarthur, Ra | |
Novel potent sigma-1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives | 1-gen-1996 | Berardi, Francesco; Giudice, G.; Perrone, Roberto; Tortorella, V.; Govoni, S.; Lucchi, L. | |
New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives | 1-gen-1996 | Berardi, Francesco; Colabufo, Nicola Antonio; Giudice, G.; Perrone, Roberto; Tortorella, V.; Govoni, S.; Lucchi, L. | |
Structure-activity relationship studies on 5-HT1A receptor affinity of 1-phenyl-4-[(alpha- or beta- tetralinyl)-alkyl]piperazines. 4 | 1-gen-1996 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V; Fornaretto, Mg; Caccia, C; Mcarthur, Ra | |
1-(2-Methoxyphenyl)-4-alkylpiperazines: effect of the N-4 substituent on the affinity and selectivity for dopamine D4 receptor | 1-gen-1997 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V. | |
5-HT3 and 5-HT4 receptor affinities of naphtho[1,2-d]thiazole derivatives with various basic side chains | 1-gen-1997 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V. | |
Synthesis of arylpiperazines with a terminal naphthothiazole group and their evaluation on 5-HT, DA and alpha receptors | 1-gen-1997 | Perrone, Roberto; Berardi, Francesco; Colabufo, N. A. A.; Tortorella, V.; Fornaretto, M.; Caccia, C.; Mcarthur, R. A. | |
4-[omega-Tetralin-1-yl]-1-benzylpiperazines and related compounds as 5-HT1A/D-2 ligands | 1-gen-1997 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Lograno, M.; Tortorella, V. | |
N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand | 1-gen-1998 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, | |
N-omega-(Tetralin-1-yl)alkyl Derivatives of 3,3-Dimethylpiperidine Are Highly Potent and Selective sigma-1 or sigma-2 Ligands | 1-gen-1998 | Berardi, Francesco; Santoro, S.; Perrone, Roberto; Tortorella, V.; Govoni, S.; Lucchi, L. | |
1-Aryl-4-[N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5 | 1-gen-1999 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V. | |
Preparation of Carbon-11 labelled N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a radioligand with picomolar affinity for dopamine D4 receptors. | 1-gen-1999 | Langer, O; Halldin, C; Chou, Y; Sandell, J; Swahn, C; Nagren, K; Perrone, R; Berardi, Francesco; Leopoldo, Marcello; Farde, L. | |
2-(Aryloxy)ethylamine derivatives: ring opened congeners of long chain 1-arylpiperazines with high 5-HT1A receptor affinity and selectivity versus D2 and a1 receptors | 1-gen-1999 | Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Leopoldo, Marcello; Tortorella, V. | |
Le applicazioni della chimica farmaceutica | 1-gen-2000 | Altomare, Cosimo Damiano; Berardi, Francesco; Carotti, Angelo; Casini, G; Catalano, Alessia; Ferappi, M; Franchini, C; Lentini, Giovanni; Liso, G; Loiodice, Fulvio; Perrone, R; Tangari, N; Tortorella, Paolo; Trapani, G; revisore TORTORELLA, V. |
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