An outbreak of canine infectious respiratory disease (CIRD) associated to canine pneumovirus (CnPnV) infection is reported. The outbreak occurred in a shelter of the Apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal discharge with no evidence of fever. The full-genomic characterisation showed that the causative agent (strain Bari/100-12) was closely related to CnPnVs that have been recently isolated in the USA, as well as to murine pneumovi-rus (MVP), which is responsible for respiratory disease in mice. The present study represents a use-ful contribution to the knowledge of the pathogenic potential of CnPnV and its association to CIRD in dogs. Further studies will elucidate the pathogenicity and epidemiology of this novel pneumovirus, thus addressing the eventual need for specific vaccines.

Canine infectious respiratory disease associated to Canine pneumovirus infection [Malattia respiratoria del cane associata ad infezione da Canine pneumovirus: Prima segnalazione in Italia]

DECARO, Nicola
;
MARI, VIVIANA;LAROCCA, VITTORIO;LOSURDO, MICHELE;OCCHIOGROSSO, Leonardo;MARTELLA, Vito;BUONAVOGLIA, Canio
2014-01-01

Abstract

An outbreak of canine infectious respiratory disease (CIRD) associated to canine pneumovirus (CnPnV) infection is reported. The outbreak occurred in a shelter of the Apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal discharge with no evidence of fever. The full-genomic characterisation showed that the causative agent (strain Bari/100-12) was closely related to CnPnVs that have been recently isolated in the USA, as well as to murine pneumovi-rus (MVP), which is responsible for respiratory disease in mice. The present study represents a use-ful contribution to the knowledge of the pathogenic potential of CnPnV and its association to CIRD in dogs. Further studies will elucidate the pathogenicity and epidemiology of this novel pneumovirus, thus addressing the eventual need for specific vaccines.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/166725
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