Organic thin film transistor (OTFT) technology can be implemented to develop cost-effective and label-free bio-affinity sensor chips, having a field-effect transport directly coupled to a bio-sensing process, useful to high-throughput testing and point-of-care applications. Biological recognition elements such as antibodies or other proteins can be integrated in OTFT devices to confer specificity. In this study the use of lipid bilayers as support for biomolecules immobilization is investigated. Preliminary results in terms of electrical resistance and capacitance of the lipid bilayers are presented.

Use of lipid bilayers as support for biomolecules integration in OTFT biosensors

LIGONZO, Teresa;COLELLA, Matilde;PALAZZO, Gerardo;TORSI, Luisa
2010-01-01

Abstract

Organic thin film transistor (OTFT) technology can be implemented to develop cost-effective and label-free bio-affinity sensor chips, having a field-effect transport directly coupled to a bio-sensing process, useful to high-throughput testing and point-of-care applications. Biological recognition elements such as antibodies or other proteins can be integrated in OTFT devices to confer specificity. In this study the use of lipid bilayers as support for biomolecules immobilization is investigated. Preliminary results in terms of electrical resistance and capacitance of the lipid bilayers are presented.
2010
978-142446391-6
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/131116
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