Thin coatings were deposited in high fragmentation regimes from RF (13.56 MHz) glow discharges fed with acrylic acid vapours. These coatings were characterized by a low surface density of COOH groups and resulted homogeneous and very stable in water. PET coated samples were used for the covalent immobilization of RGD peptide via a his amine spacer arm, using COOH surface functionalities as anchor groups. Substrates from the different steps of RGD immobilization were used for cell adhesion assays with 3T3 fibroblasts.

Immobilization of RGD peptides on stable plasma-deposited acrylic acid coatings for biomedical devices

FAVIA, Pietro;
2005-01-01

Abstract

Thin coatings were deposited in high fragmentation regimes from RF (13.56 MHz) glow discharges fed with acrylic acid vapours. These coatings were characterized by a low surface density of COOH groups and resulted homogeneous and very stable in water. PET coated samples were used for the covalent immobilization of RGD peptide via a his amine spacer arm, using COOH surface functionalities as anchor groups. Substrates from the different steps of RGD immobilization were used for cell adhesion assays with 3T3 fibroblasts.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/106399
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 61
  • ???jsp.display-item.citation.isi??? 59
social impact